Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344836 | 0.85 | KDM4E (0.45) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL13524441 | 0.78 | KDM4E (0.40) | KDM4EMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28063083 | 0.75 | KDM4E (0.55) | KDM4EMEN1KMT2AL3MBTL1CETP | |
| SCHEMBL31643643 | 0.75 | ALDH1A1 (0.52) | KDM4EMEN1KMT2AGFERSMN1; SMN2 | |
| SCHEMBL8806924 | 0.75 | CA12 (0.59) | KDM4EMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10766865 | 0.73 | KDM4E (0.47) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL10344854 | 0.73 | LMNA (0.45) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4013508 | 0.71 | GAA (0.56) | KDM4EMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1429976 | 0.71 | RAB9A (0.56) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL30805788 | 0.71 | CA12 (0.57) | KDM4EMEN1KMT2AGFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190971-A | SUBSTITUTED DIBENZ-OXA-THIOCINONES, -12-OXIDES AND -12,12-DIOXIDES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |