Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10810203 | 0.89 | ALDH1A1 (0.42) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL10809288 | 0.87 | MAPT (0.46) | ALDH1A1GAAMAPTTDP1KDM4E | |
| SCHEMBL4038402 | 0.85 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTTDP1KDM4E | |
| SCHEMBL3979308 | 0.85 | MEN1 (0.36) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL17221734 | 0.85 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4ECA12CA1 | |
| SCHEMBL14494974 | 0.83 | KDM4E (0.40) | ALDH1A1GAAMAPTKDM4ECA12 | |
| SCHEMBL10344836 | 0.83 | KDM4E (0.45) | ALDH1A1GAAMAPTTDP1KDM4E | |
| SCHEMBL3986627 | 0.82 | CA12 (0.56) | GAAMAPTKDM4ECA12CA1 | |
| SCHEMBL10808619 | 0.81 | CYP1A2 (0.50) | ALDH1A1MAPTTDP1KDM4EKMT2A | |
| SCHEMBL1097144 | 0.78 | BRD4 (0.49) | ALDH1A1GAAKDM4EKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210857-A1 | Process for the preparation of alkyl 2-carboalkoxy-3,4-dialkoxybenzenecarbamates | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-02-04 | — | — | EP | claimed |
| US-4617417-A | Alkyl 2-carboalkoxy-3,4-dialkoxybenzenecarbamates and process for their preparation | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-10-14 | — | — | US | claimed |
| EP-2763539-B1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LTD (GB) | 2017-02-08 | — | — | EP | disclosed |
| US-9340556-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2016-05-17 | — | — | US | disclosed |
| US-9340556-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2016-05-17 | — | — | US | disclosed |
| CN-104039152-A | Antibacterial compounds | GLAXO GROUP LTD | 2014-09-10 | — | — | CN | disclosed |
| US-20140249126-A1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2014-09-04 | — | — | US | disclosed |
| US-20140249126-A1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2014-09-04 | — | — | US | disclosed |
| EP-2763539-A1 | ANTIBACTERIAL COMPOUNDS | Glaxo Group Limited (GB) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013052568-A1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-04-11 | — | — | WO | disclosed |
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |
| EP-1401443-A4 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORP (US) | 2005-10-26 | — | — | EP | disclosed |
| US-20040147739-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-07-29 | — | — | US | disclosed |
| EP-1401443-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002098424-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-12-12 | — | — | WO | disclosed |
| EP-0210857-A1 | Process for the preparation of alkyl 2-carboalkoxy-3,4-dialkoxybenzenecarbamates | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-02-04 | — | — | EP | disclosed |
| US-4617417-A | Alkyl 2-carboalkoxy-3,4-dialkoxybenzenecarbamates and process for their preparation | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | RPL5, RPL7, RPL35 | ALDH1A1 1494/4885GAA 197/4885MAPT 4204/4885 |
| US-20140249126-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, PEPD, ABCB11 | ALDH1A1 3841/4885GAA 712/4885MAPT 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.