Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862422 | 0.91 | MEN1 (0.36) | L3MBTL1 | |
| SCHEMBL9502745 | 0.81 | THRA (0.41) | — | |
| SCHEMBL3242474 | 0.80 | TSHR (0.40) | L3MBTL1 | |
| SCHEMBL7871491 | 0.79 | THRA (0.49) | ENPP2 | |
| SCHEMBL10411867 | 0.79 | THRA (0.49) | ENPP2 | |
| SCHEMBL27082092 | 0.79 | THRA (0.49) | ENPP2 | |
| SCHEMBL11507345 | 0.77 | KCNH2 (0.32) | — | |
| SCHEMBL14889733 | 0.77 | LTA4H (0.32) | — | |
| SCHEMBL333671 | 0.75 | CA12 (0.41) | CYP2D6L3MBTL1 | |
| SCHEMBL3784692 | 0.74 | CHRNA7 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193228-B1 | PROCESS FOR PRODUCING OF 4-(2-METHOXYETHYL)-PHENYLGLYCIDYL ETHER AND/OR METOPROLOL | GIST-BROCADES N.V. (NL) | 1989-11-02 | — | — | EP | claimed |
| CN-86100965-A | Produce 4-(2-methoxyethyl)-phenylglycidyl ether and (or) method of metoprolol | — | 1986-10-01 | — | — | CN | claimed |
| EP-0193228-A1 | Process for producing of 4-(2-methoxyethyl)-phenylglycidyl ether and/or metoprolol | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | claimed |
| JP-61254194-A | — | — | None | — | — | JP | disclosed |
| US-4956284-A | Process for producing 4-(2-methoxyethyl)-phenyl-glycidyl ether and/or metoprolol | GIST-BROCADES N.V. (NL) | 1990-09-11 | — | — | US | disclosed |
| EP-0193227-B1 | PROCESS FOR THE PREPARATION OF ARYLGLYCIDYL ETHERS AND 3-SUBSTITUTED 1-ALKYLAMINO-2-PROPANOLS | GIST-BROCADES N.V. (NL) | 1990-04-11 | — | — | EP | disclosed |
| EP-0193228-B1 | PROCESS FOR PRODUCING OF 4-(2-METHOXYETHYL)-PHENYLGLYCIDYL ETHER AND/OR METOPROLOL | GIST-BROCADES N.V. (NL) | 1989-11-02 | — | — | EP | disclosed |
| EP-0193228-B1 | PROCESS FOR PRODUCING OF 4-(2-METHOXYETHYL)-PHENYLGLYCIDYL ETHER AND/OR METOPROLOL | GIST-BROCADES N.V. (NL) | 1989-11-02 | — | — | EP | disclosed |
| CN-86102227-A | The preparation method of 1-alkylamino-2-propyl alcohol that arylolycidyl ethers and 3-replace | — | 1987-02-04 | — | — | CN | disclosed |
| JP-S61254194-A | PRODUCTION OF 4-(2-METHOXYETHYL)-PHENYLGLYCIDYL ETHER AND/ORMETHOPRROLOLE | GIST BROCADES NV | 1986-11-11 | — | — | JP | disclosed |
| CN-86100965-A | Produce 4-(2-methoxyethyl)-phenylglycidyl ether and (or) method of metoprolol | — | 1986-10-01 | — | — | CN | disclosed |
| CN-86100965-A | Produce 4-(2-methoxyethyl)-phenylglycidyl ether and (or) method of metoprolol | — | 1986-10-01 | — | — | CN | disclosed |
| CN-86100965-A | Produce 4-(2-methoxyethyl)-phenylglycidyl ether and (or) method of metoprolol | — | 1986-10-01 | — | — | CN | disclosed |
| EP-0193228-A1 | Process for producing of 4-(2-methoxyethyl)-phenylglycidyl ether and/or metoprolol | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | disclosed |
| EP-0193227-A1 | Process for the preparation of arylglycidyl ethers and 3-substituted 1-alkylamino-2-propanols | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | disclosed |
| EP-0193228-A1 | Process for producing of 4-(2-methoxyethyl)-phenylglycidyl ether and/or metoprolol | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | disclosed |
| EP-0193228-A1 | Process for producing of 4-(2-methoxyethyl)-phenylglycidyl ether and/or metoprolol | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | disclosed |