Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SOD1 | P00441 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502745 | 0.83 | THRA (0.41) | HPGDSLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL14889733 | 0.82 | LTA4H (0.32) | TSHR | |
| SCHEMBL10411867 | 0.81 | THRA (0.49) | SLC6A2SLC6A4SLC6A3TP53LPL | |
| SCHEMBL7871491 | 0.81 | THRA (0.49) | SLC6A2SLC6A4SLC6A3TP53LPL | |
| SCHEMBL27082092 | 0.81 | THRA (0.49) | SLC6A2SLC6A4SLC6A3TP53LPL | |
| SCHEMBL4813260 | 0.81 | NPSR1 (0.39) | TSHRHPGD | |
| SCHEMBL10345289 | 0.80 | ACACB (0.36) | L3MBTL1 | |
| SCHEMBL3784692 | 0.79 | CHRNA7 (0.39) | TDP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8847061 | 0.79 | MGLL (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10586992 | 0.78 | ALDH1A1 (0.40) | TSHRHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184364-B1 | COMB-SHAPED DIOL, WATER-SOLUBLE POLYURETHANE, AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2010-07-28 | — | — | EP | disclosed |
| EP-0324569-B1 | Process for preparing functionalized polymeric compositions | ROHM & HAAS (US) | 2004-10-27 | — | — | EP | disclosed |
| US-6646093-B2 | Extruding auxiliary for cement materials, a mortar thickening agent, an underwater concrete thickening agent, a ceramics forming binder and a moisturizer for hair cosmetics; water and shape retention. | MITSUI CHEMICALS, INC. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-6515050-B1 | An extruding auxiliary using the above novel water-soluble polyurethane; additive for underwater concrete | MITSUI CHEMICALS, INC. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20020045724-A1 | Water-souluble polyurthane having comb-shaped hydrophobic group and application thereof | MITSUI TAKEDA CHEMICALS, INC. (JP) | 2002-04-18 | — | — | US | disclosed |
| EP-1184364-A1 | COMB-SHAPED DIOL, WATER-SOLUBLE POLYURETHANE, AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-5130369-A | Polymerization of a monomer with a chain transfer agent and a second monomer with the monomers interacting | ROHM AND HAAS COMPANY (US) | 1992-07-14 | — | — | US | disclosed |
| US-3953604-A | INHALATION, ANTI-ASTHMA | MILES LABORATORIES, INC. (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045724-A1 | Water-souluble polyurthane having comb-shaped hydrophobic group and application thereof | BMI1, ASH2L, HAT1 | TSHR 4441/4885MAPK1 4510/4885ATM 2706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.