Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411867 | 1.00 | THRA (0.49) | THRATHRBHTR2ASPHK1SPHK2 | |
| SCHEMBL27082092 | 1.00 | THRA (0.49) | THRATHRBHTR2ASPHK1SPHK2 | |
| SCHEMBL9502745 | 0.94 | THRA (0.41) | THRATHRBHTR2ASPHK1SPHK2 | |
| SCHEMBL8046083 | 0.83 | SPHK2 (0.46) | THRATHRBHTR2ASPHK1SPHK2 | |
| SCHEMBL8660244 | 0.83 | SPHK2 (0.46) | THRATHRBHTR2ASPHK1SPHK2 | |
| SCHEMBL11862422 | 0.82 | MEN1 (0.36) | THRATHRBALDH1A1TP53CYP3A4 | |
| SCHEMBL27990442 | 0.81 | THRA (0.43) | THRATHRBHTR2ASPHK1SPHK2 | |
| SCHEMBL3242474 | 0.81 | TSHR (0.40) | SLC6A2SLC6A4SLC6A3TP53LPL | |
| SCHEMBL3239492 | 0.79 | THRA (0.49) | THRATHRBHTR2ASPHK1SPHK2 | |
| SCHEMBL10345289 | 0.79 | ACACB (0.36) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010055461-A1 | METHOD FOR PRODUCING AN OPTICAL WAVEGUIDE | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 2001-12-27 | — | — | US | disclosed |
| EP-0943935-A2 | Optical waveguide and method for production thereof | Nippon Telegraph and Telephone Corporation (JP) | 1999-09-22 | — | — | EP | disclosed |