SCHEMBL10345455

SCHEMBL10345455

Cc1ccc(SCCOc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 4/20 0.58
DRD4 P21917 4/20 0.58
DRD3 P35462 3/20 0.57
MAPT P10636 4/20 0.56
TP53 P04637 1/20 0.56
AR P10275 2/20 0.50
CHRNB2 P17787 1/20 0.50
CHRNB4 P30926 1/20 0.50
CHRNA3 P32297 1/20 0.50
CHRNA7 P36544 1/20 0.50
CHRNA4 P43681 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
LSS P48449 1/20 0.49
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
POLB P06746 1/20 0.47
ALOX15 P16050 1/20 0.47
LMNA P02545 2/20 0.46
ALDH1A1 P00352 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9808032 0.90 DRD2 (0.69) DRD2DRD4DRD3MAPTTP53
SCHEMBL10345792 0.90 DRD2 (0.68) DRD2DRD4DRD3MAPTTP53
SCHEMBL6939490 0.88 CHRNB2 (0.53) DRD2DRD4DRD3MAPTCHRNB2
SCHEMBL10345794 0.87 SMN1; SMN2 (0.58) DRD2DRD4DRD3MAPTTP53
SCHEMBL10345731 0.84 ALDH1A1 (0.51) DRD2DRD4MAPTCHRNB2CHRNB4
SCHEMBL9808218 0.83 LSS (0.62) DRD2DRD4DRD3CHRNB2CHRNB4
SCHEMBL10345823 0.81 LMNA (0.55) DRD2DRD4DRD3MAPTTP53
SCHEMBL9768860 0.81 NPC1 (0.58) DRD2DRD4DRD3MAPTTP53
SCHEMBL10345812 0.80 DRD2 (0.70) DRD2DRD4DRD3MAPTTP53
SCHEMBL20005618 0.80 DRD2 (0.57) DRD2DRD4DRD3MAPTAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0222343-B1 RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP disclosed
US-4792542-A CONTAINING AN AROMATIC SULFIDE FUJI PHOTO FILM CO., LTD. (JP) 1988-12-20 US disclosed
EP-0222343-A2 Recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-05-20 EP disclosed