Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19284163 | 0.74 | MGLL (0.40) | LMNATSHRMAPK1P2RX4 | |
| SCHEMBL3732224 | 0.73 | P2RX4 (0.35) | ALDH1A1LMNATSHRMAPK1P2RX4 | |
| SCHEMBL10720430 | 0.72 | P2RX4 (0.33) | LMNATSHRMAPK1P2RX4 | |
| SCHEMBL693565 | 0.70 | LMNA (0.32) | LMNATSHRMAPK1P2RX4 | |
| SCHEMBL1249107 | 0.69 | MTNR1A (0.39) | ALDH1A1LMNATSHRMAPK1P2RX4 | |
| SCHEMBL1246144 | 0.69 | LMNA (0.39) | ALDH1A1LMNATSHRMAPK1P2RX4 | |
| SCHEMBL11498008 | 0.67 | — | — | |
| SCHEMBL6312853 | 0.66 | LMNA (0.41) | LMNATSHRMAPK1P2RX4 | |
| SCHEMBL7518490 | 0.65 | LMNA (0.39) | ALDH1A1LMNATSHRMAPK1P2RX4 | |
| SCHEMBL7414781 | 0.65 | LMNA (0.35) | LMNATSHRMAPK1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230755-B1 | 1-PHENYL-3-BENZAZEPINES | SMITHKLINE BEECHAM CORPORATION (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4707483-A | 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders | SMITHKLINE BECKMAN CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0230755-A1 | 1-Phenyl-3-benzazepines | SMITHKLINE BEECHAM CORPORATION (US) | 1987-08-05 | — | — | EP | disclosed |