SCHEMBL10347616

SCHEMBL10347616

O=[N+]([O-])c1ccc(-c2ccc3c(nnn3[Ag])c2O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GYS1 P13807 2/20 0.42
▸ LMNA P02545 3/20 0.39
▸ RECQL P46063 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ HTT P42858 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ GAA P10253 4/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ RAD51 Q06609 1/20 0.36
▸ MAPK1 P28482 2/20 0.35
▸ POLB P06746 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ XDH P47989 1/20 0.35
▸ MGAM O43451 2/20 0.34
▸ SI P14410 2/20 0.34
▸ MGAM2 Q2M2H8 2/20 0.34
▸ AMY1A P0DUB6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10347701 0.84 MAPK1 (0.39) GYS1MEN1KMT2ASMN1; SMN2GAA
SCHEMBL10347622 0.80 LMNA (0.35) LMNAHTTSMN1; SMN2KDM4EPOLB
SCHEMBL10348189 0.79 HDAC4 (0.37) LMNAMEN1KMT2AGAAMAPK1
SCHEMBL10347786 0.77 GPR35 (0.42) LMNARECQLMEN1KMT2AHTT
SCHEMBL8424662 0.71 ALDH1A1 (0.46) MEN1KMT2AGAACYP1A2CYP3A4
SCHEMBL10827736 0.70 MAPT (0.38) GYS1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL6052044 0.70 GYS1 (0.50) GYS1LMNARECQLMEN1KMT2A
Silver SCHEMBL9171322 0.69 GYS1 (0.49) GYS1LMNARECQLMEN1KMT2A
SCHEMBL9171329 0.69 GYS1 (0.49) GYS1LMNARECQLMEN1KMT2A
SCHEMBL28476433 0.69 GPR35 (0.52) GYS1LMNARECQLMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136142-B1 THERMALLY DEVELOPABLE, LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-04-11 — — EP disclosed
US-4584267-A SILVER HALIDE, SILVER SALT, REDUCING AGENT, AND BINDER OF GELATIN OR DERIVATIVE AND POLYVINYL ALCOHOL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-22 — — US disclosed
EP-0157639-A2 Heat-developable multilayered color photo-sensitive material KONICA CORPORATION (JP) 1985-10-09 — — EP disclosed
EP-0136142-A2 Thermally developable, light-sensitive material KONICA CORPORATION (JP) 1985-04-03 — — EP disclosed
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