Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347509 | 0.83 | HTR1A (0.41) | SIGMAR1 | |
| SCHEMBL10347239 | 0.80 | DRD2 (0.53) | — | |
| Bromide SCHEMBL10347450 | 0.79 | DRD2 (0.52) | — | |
| Hydrochloric Acid SCHEMBL10870298 | 0.75 | DRD2 (0.48) | — | |
| SCHEMBL10347485 | 0.73 | DRD2 (0.48) | — | |
| SCHEMBL9689118 | 0.72 | DRD2 (0.40) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9688926 | 0.72 | HTR1A (0.46) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9689630 | 0.70 | KDM4E (0.40) | SIGMAR1EBPTMEM97 | |
| SCHEMBL10959824 | 0.70 | AOC3 (0.48) | SIGMAR1EBPTMEM97 | |
| SCHEMBL10753475 | 0.70 | AOC3 (0.51) | SIGMAR1EBPTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175525-B1 | 7-[2-(Dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones | SMITHKLINE BEECHAM CORPORATION (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0175525-A1 | 7-[2-(Dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones | SMITHKLINE BEECHAM CORPORATION (US) | 1986-03-26 | — | — | EP | disclosed |
| US-4554287-A | Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones | SMITHKLINE BECKMAN CORPORATION (US) | 1985-11-19 | — | — | US | disclosed |