Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294913 | 0.86 | ALDH1A1 (0.46) | ALDH1A1GPR139LMNAHTTHDAC1 | |
| SCHEMBL7723692 | 0.85 | ALDH1A1 (0.46) | ALDH1A1GPR139LMNAHTT | |
| Hydrochloric Acid SCHEMBL4329941 | 0.85 | ALDH1A1 (0.45) | ALDH1A1GPR139LMNAHTTHDAC1 | |
| SCHEMBL27509786 | 0.83 | ALDH1A1 (0.59) | ALDH1A1GPR139LMNAHTTESR1 | |
| SCHEMBL1567110 | 0.77 | LMNA (0.61) | LMNAHDAC1MEN1KMT2A | |
| SCHEMBL1567121 | 0.77 | PRCP (0.49) | ALDH1A1LMNAHTTMEN1PKM | |
| SCHEMBL28482389 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GPR139HDAC1ESR1 | |
| SCHEMBL7191170 | 0.75 | HSD17B10 (0.54) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL15200214 | 0.75 | GPR139 (0.50) | ALDH1A1GPR139HTTHDAC1SMN1; SMN2 | |
| SCHEMBL11468737 | 0.75 | PKM (0.42) | ALDH1A1GPR139LMNACNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962146-A | 3-O-glycosyl 16-membered macrolide antibacterials and related derivatives | SCHERING CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0362267-A1 | 3-O-GLYCOSYL 16-MEMBERED MACROLIDE ANTIBACTERIALS AND RELATED DERIVATIVES | SCHERING CORPORATION (US) | 1990-04-11 | — | — | EP | disclosed |
| WO-1988008426-A1 | 3-O-GLYCOSYL 16-MEMBERED MACROLIDE ANTIBACTERIALS AND RELATED DERIVATIVES | SCHERING CORPORATION (US) | 1988-11-03 | — | — | WO | disclosed |