SCHEMBL10348248

SCHEMBL10348248

CN(C)C(=O)COC(=O)CNc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.45
POLB P06746 2/20 0.43
FFAR1 O14842 1/20 0.41
ALDH1A1 P00352 4/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
NPC1 O15118 1/20 0.40
HPGD P15428 1/20 0.40
AGTR1 P30556 1/20 0.40
ATM Q13315 1/20 0.39
PPID Q08752 1/20 0.39
PKM P14618 1/20 0.39
ELANE P08246 1/20 0.39
STAT3 P40763 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62893 0.82 POLB (0.60) SMN1; SMN2POLBALDH1A1RAB9AMEN1
SCHEMBL1783192 0.81 PKM (0.46) SMN1; SMN2FFAR1ALDH1A1RAB9AMEN1
Hydrochloric Acid SCHEMBL133175 0.80 POLB (0.59) SMN1; SMN2POLBALDH1A1RAB9AMEN1
Hydrochloric Acid SCHEMBL1781771 0.80 PKM (0.45) SMN1; SMN2FFAR1ALDH1A1RAB9AMEN1
Alcohol SCHEMBL28628021 0.79 POLB (0.57) SMN1; SMN2POLBALDH1A1RAB9AMEN1
Acetic Acid SCHEMBL28661029 0.79 POLB (0.57) SMN1; SMN2POLBALDH1A1RAB9AMEN1
Hydrochloric Acid SCHEMBL10891081 0.78 ALDH1A1 (0.45) SMN1; SMN2POLBFFAR1ALDH1A1RAB9A
SCHEMBL11732203 0.78 POLB (0.56) SMN1; SMN2POLBALDH1A1RAB9AMEN1
SCHEMBL11726671 0.76 ALDH1A1 (0.44) SMN1; SMN2POLBFFAR1ALDH1A1RAB9A
Sulfuric Acid SCHEMBL28065986 0.76 POLB (0.55) SMN1; SMN2POLBALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364016-A1 Polyphosphazene polymers and their preparation Stichting Biomaterials Science Center, VU, "BSC-VU" (NL) 1990-04-18 EP disclosed