SCHEMBL1783192

SCHEMBL1783192

CN(C)C(=O)CNc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.46
RAB9A P51151 3/20 0.45
ALDH1A1 P00352 3/20 0.45
LMNA P02545 2/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
NPC1 O15118 2/20 0.44
CYP2D6 P10635 1/20 0.44
OPRK1 P41145 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HPGD P15428 1/20 0.44
AGTR1 P30556 1/20 0.44
ERCC1 P07992 1/20 0.44
ERCC4 Q92889 1/20 0.44
GAA P10253 2/20 0.42
KDM4E B2RXH2 1/20 0.42
AKR1C3 P42330 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1781771 0.98 PKM (0.45) PKMRAB9AALDH1A1LMNAKMT2A
SCHEMBL31262950 0.82 CA1 (0.44) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL807665 0.82 MAPT (0.48) RAB9AALDH1A1KMT2AMEN1MAPT
SCHEMBL10348248 0.81 SMN1; SMN2 (0.45) PKMRAB9AALDH1A1LMNAKMT2A
SCHEMBL11258990 0.81 CA12 (0.62) PKMRAB9AALDH1A1LMNAKMT2A
SCHEMBL31262962 0.81 TSHR (0.55) PKMRAB9AALDH1A1LMNAKMT2A
SCHEMBL31263081 0.81 MAPT (0.44) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL20762355 0.81 CA12 (0.43) RAB9AALDH1A1NPC1SMN1; SMN2HPGD
SCHEMBL4493412 0.81 CA12 (0.46) PKMRAB9ALMNAKMT2AMEN1
SCHEMBL28904888 0.81 ALDH1A1 (0.47) RAB9AALDH1A1MAPTNPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702000-A1 ALKYLATION PROCESS University of Liverpool (GB) 2026-03-04 EP disclosed
US-12447207-B2 Human cytomegalovirus gB polypeptide PFIZER INC. (US) 2025-10-21 US disclosed
WO-2025203556-A1 PROGRAM, DEBUGGING DEVICE, DEBUGGING SYSTEM, AND DEBUGGING METHOD 三菱電機株式会社 2025-10-02 WO disclosed
US-20250066562-A1 METHOD AND MATERIAL FOR DIFFERENTIATED SEQUESTRATION OF SUBSTANCES OF DIFFERENT SUBSTANCE GROUPS WITH THE AID OF HYDROGELS CONTAINING SULPHATED OR SULPHONATED COMPONENTS LEIBNIZ-INSTITUT FÜR POLYMERFORSCHUNG E.V. (DE) 2025-02-27 US disclosed
US-20250066561-A1 METHOD AND MATERIAL FOR DIFFERENTIATED SEQUESTRATION OF SUBSTANCES OF DIFFERENT SUBSTANCE GROUPS WITH THE AID OF HYDROGELS CONTAINING SULPHATED OR SULPHONATED COMPONENTS LEIBNIZ-INSTITUT FÜR POLYMERFORSCHUNG E.V. (DE) 2025-02-27 US disclosed
WO-2025028235-A1 IMAGING ELEMENT AND IMAGING DEVICE ソニーセミコンダクタソリューションズ株式会社 2025-02-06 WO disclosed
WO-2024224034-A1 ALKYLATION PROCESS THE UNIVERSITY OF LIVERPOOL (GB) 2024-10-31 WO disclosed
US-20240299587-A1 NOVEL DRUGGABLE REGIONS IN THE HUMAN CYTOMEGALOVIRUS GLYCOPROTEIN B POLYPEPTIDE AND METHODS OF USE THEREOF PFIZER (US) 2024-09-12 US disclosed
US-20240228628-A9 ANTIBODIES TARGETING FLT3 AND USE THEREOF DRAGONFLY THERAPEUTICS INC (US) 2024-07-11 US disclosed
CN-117964504-A Preparation method of gem-difluoroallylglycine or polypeptide derivative 南京林业大学 2024-05-03 CN disclosed
US-20070032433-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION CORVAS INTERNATIONAL, LTD. 2007-02-08 US disclosed
US-20060205672-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION (US) 2006-09-14 US disclosed
US-7012066-B2 Peptides as NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION (US) 2006-03-14 US disclosed
CN-1633446-A Novel peptides as inhibitors of hepatitis C virus NS 3-serine protease SCHERING CORP (US) 2005-06-29 CN disclosed
US-20040254117-A9 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus DENDREON PHARMACEUTICALS LLC 2004-12-16 US disclosed
EP-1481000-A2 NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS SCHERING CORPORATION (US) 2004-12-01 EP disclosed
EP-1385870-A2 PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS Schering Corporation (US) 2004-02-04 EP disclosed
US-20030216325-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus SAKSENA ANIL K 2003-11-20 US disclosed
WO-2003062265-A2 NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS SCHERING CORPORATION (US) 2003-07-31 WO disclosed
WO-2002008244-A2 PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS SCHERING CORPORATION (US) 2002-01-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060205672-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus HPN, TMPRSS15, VIP PKM 3364/4885RAB9A 2106/4885ALDH1A1 2369/4885
US-20030216325-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus HPN, TMPRSS15, VIP PKM 3364/4885RAB9A 2106/4885ALDH1A1 2369/4885
US-12447207-B2 Human cytomegalovirus gB polypeptide GBA3, HBB, PDGFA PKM 3851/4885RAB9A 1275/4885ALDH1A1 4825/4885
US-20240299587-A1 NOVEL DRUGGABLE REGIONS IN THE HUMAN CYTOMEGALOVIRUS GLYCOPROTEIN B POLYPEPTIDE AND METHODS OF USE THEREOF HAVCR2, LGALS3BP, GBA3 PKM 4113/4885RAB9A 1463/4885ALDH1A1 3914/4885
US-20070032433-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus HPN, TMPRSS15, VIP PKM 3364/4885RAB9A 2106/4885ALDH1A1 2369/4885
US-20040254117-A9 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus HPN, TMPRSS15, VIP PKM 3364/4885RAB9A 2106/4885ALDH1A1 2369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.