SCHEMBL10348335

SCHEMBL10348335

CNC(=S)NNc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 9/20 0.63
MAPT P10636 6/20 0.63
ALDH1A1 P00352 8/20 0.56
TDP1 Q9NUW8 4/20 0.56
MAPK1 P28482 2/20 0.56
SMN1; SMN2 Q16637 4/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
ALOX5 P09917 2/20 0.52
CYP3A4 P08684 2/20 0.52
TSHR P16473 1/20 0.52
KMT2A Q03164 5/20 0.51
MEN1 O00255 4/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 1/20 0.50
NOX1 Q9Y5S8 1/20 0.50
TAS2R38 P59533 2/20 0.48
HSD17B10 Q99714 1/20 0.48
LMNA P02545 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2885482 0.86 GAA (0.67) GAAMAPTALDH1A1TDP1MAPK1
SCHEMBL11414331 0.81 GAA (0.47) GAAMAPTALDH1A1TDP1MAPK1
SCHEMBL2231449 0.80 GAA (0.78) GAAMAPTALDH1A1TDP1MAPK1
SCHEMBL7840142 0.79 PTGS2 (0.48) GAAMAPTALDH1A1TDP1MAPK1
SCHEMBL11412488 0.78 GAA (0.58) GAAMAPTALDH1A1TDP1MAPK1
SCHEMBL23812525 0.77 GAA (0.84) GAAMAPTALDH1A1SMN1; SMN2CYP1A2
SCHEMBL1276402 0.77 GAA (0.84) GAAMAPTALDH1A1SMN1; SMN2CYP1A2
SCHEMBL3635635 0.77 GAA (0.55) GAAMAPTALDH1A1TDP1MAPK1
SCHEMBL11684405 0.76 ALDH1A1 (0.77) GAAMAPTALDH1A1SMN1; SMN2CYP1A2
SCHEMBL11317515 0.75 MAPT (0.76) GAAMAPTALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112028911-A Zinc complex taking 2-benzoylpyridine thiosemicarbazone as ligand and synthetic method and application thereof 广西师范大学 2020-12-04 CN disclosed
EP-0144990-B1 PROCESS FOR PREPARING SILVER HALIDE EMULSION FUJI PHOTO FILM CO., LTD. (JP) 1990-04-25 EP disclosed
US-4675276-A MESIONIC 1,2,4-TRIAZOLIUM-3-THIOLATE; ANTIFOGGING, HIGH TEMPE RATURE QUICK PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 1987-06-23 US disclosed
US-4665017-A GRAIN GROWTH PROMOTOR AND INHIBITOR FUJI PHOTO FILM CO., LTD. (JP) 1987-05-12 US disclosed
US-4631253-A INCREASED GRAIN SIZE WITH NOVEL ODORLESS SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1986-12-23 US disclosed
US-4582775-A PREVENTING FOG WHILE MAINTAINING SENSITIVITY AND RATE OF DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 1986-04-15 US disclosed
EP-0144990-A2 Process for preparing silver halide emulsion FUJI PHOTO FILM CO., LTD. (JP) 1985-06-19 EP disclosed