SCHEMBL10348408

SCHEMBL10348408

CNC(=S)NN1CCCC1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
BRD4 O60885 1/20 0.38
BRD2 P25440 1/20 0.38
MEN1 O00255 1/20 0.34
LMNA P02545 4/20 0.33
ALDH1A1 P00352 3/20 0.33
CHRM2 P08172 2/20 0.33
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
APEX1 P27695 2/20 0.33
PMP22 Q01453 2/20 0.33
TSHR P16473 2/20 0.33
CYP2D6 P10635 1/20 0.33
ALOX12 P18054 1/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33
PIK3CD O00329 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31283180 0.77 BRD4 (0.35) KMT2ABRD4BRD2LMNAALDH1A1
SCHEMBL28039806 0.77 BRD4 (0.35) KMT2ABRD4BRD2LMNAALDH1A1
SCHEMBL5476941 0.75 BRD4 (0.41) KMT2ABRD4BRD2MEN1LMNA
SCHEMBL761439 0.73
SCHEMBL11884023 0.73 BRD4 (0.40) KMT2ABRD4BRD2MEN1LMNA
SCHEMBL6849692 0.72 TSHR (0.47) KMT2ABRD4BRD2MEN1LMNA
SCHEMBL10920232 0.72 LMNA (0.41) KMT2ABRD4BRD2MEN1LMNA
SCHEMBL19323075 0.70 L3MBTL1 (0.39) KMT2ABRD4BRD2LMNAALDH1A1
SCHEMBL19318547 0.70 BRD4 (0.38) KMT2ABRD4BRD2LMNAALDH1A1
SCHEMBL11656190 0.70 TSHR (0.38) KMT2ALMNAALDH1A1TSHRCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0144990-B1 PROCESS FOR PREPARING SILVER HALIDE EMULSION FUJI PHOTO FILM CO., LTD. (JP) 1990-04-25 EP disclosed
US-4675276-A MESIONIC 1,2,4-TRIAZOLIUM-3-THIOLATE; ANTIFOGGING, HIGH TEMPE RATURE QUICK PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 1987-06-23 US disclosed
US-4665017-A GRAIN GROWTH PROMOTOR AND INHIBITOR FUJI PHOTO FILM CO., LTD. (JP) 1987-05-12 US disclosed
US-4631253-A INCREASED GRAIN SIZE WITH NOVEL ODORLESS SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1986-12-23 US disclosed
US-4582775-A PREVENTING FOG WHILE MAINTAINING SENSITIVITY AND RATE OF DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 1986-04-15 US disclosed
EP-0144990-A2 Process for preparing silver halide emulsion FUJI PHOTO FILM CO., LTD. (JP) 1985-06-19 EP disclosed