SCHEMBL6849692

SCHEMBL6849692

NC(=O)NN1CCCC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
LMNA P02545 4/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA13 Q8N1Q1 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
BRD4 O60885 1/20 0.38
BRD2 P25440 1/20 0.38
ALDH1A1 P00352 5/20 0.35
KMT2A Q03164 3/20 0.35
HTT P42858 1/20 0.34
CHRM2 P08172 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8561276 0.92 TSHR (0.40) TSHRLMNACA12CA1CA2
SCHEMBL10920232 0.83 LMNA (0.41) TSHRLMNACA12CA1CA2
SCHEMBL5476941 0.81 BRD4 (0.41) TSHRLMNACA12CA1CA2
SCHEMBL11884023 0.79 BRD4 (0.40) TSHRLMNACA12CA1CA2
SCHEMBL909148 0.77 KMT2A (0.37) TSHRLMNABRD4BRD2ALDH1A1
SCHEMBL6348530 0.76 LMNA (0.36) TSHRLMNACA12CA1CA2
SCHEMBL11656190 0.76 TSHR (0.38) TSHRLMNACA12CA1CA2
SCHEMBL11752882 0.76 LMNA (0.40) TSHRLMNACA12CA1CA2
SCHEMBL19318547 0.76 BRD4 (0.38) TSHRLMNACA12CA1CA2
SCHEMBL19323075 0.76 L3MBTL1 (0.39) TSHRLMNACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830421-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1998-03-25 EP claimed
US-5665852-A USEFUL IN POWDER COATING COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 1997-09-09 US claimed
WO-1996040825-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO claimed
CN-104177951-B Anti-dazzle coating composition and its preparation and use 北京化工大学 2018-07-10 CN disclosed
CN-102869629-B Anti-glare surface treatment method and article thereof 康宁股份有限公司 2017-03-01 CN disclosed
CN-102438987-A Crystal of cyazofamid and preparation method thereof NISSAN CHEMICAL IND LTD 2012-05-02 CN disclosed
US-6776830-B2 CONTAINS POLYSACCHARIDE; GIVES RELIABLE PERFORMANCE YIELDING RAPIDLY DRYING IMAGES SEIKO EPSON CORPORATION (JP) 2004-08-17 US disclosed
US-6630599-B1 Blocked derivatives of m- or p- isopropenyl- alpha , alpha -dimethylbenzyl isocyanates, comprising reacting a meta- or a para-isopropenyl-alpha, alpha-dimethylbenzyl carbamate ester with hydroxy functional blocking group, such as CYTEC TECHNOLOGY CORP. 2003-10-07 US disclosed
US-20020185038-A1 Aqueous ink composition for use in an ink-jet printer SEIKO EPSON CORPORATION 2002-12-12 US disclosed
EP-0691953-B1 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS SEARLE & CO (US) 2000-08-02 EP disclosed
EP-0830421-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1998-03-25 EP disclosed
WO-1996040825-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO disclosed
WO-1996040825-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO disclosed
EP-0691953-A1 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1996-01-17 EP disclosed
EP-0561941-B1 N-SUBSTITUTED LACTAMS USEFUL AS CHOLECYSTOKININ ANTAGONISTS SEARLE & CO (US) 1995-01-04 EP disclosed
WO-1994022820-A1 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1994-10-13 WO disclosed
US-5314886-A N-substituted lactams useful as cholecystokinin antagonists G. D. SEARLE & CO. (US) 1994-05-24 US disclosed
EP-0561941-A1 N-SUBSTITUTED LACTAMS USEFUL AS CHOLECYSTOKININ ANTAGONISTS. SEARLE & CO (US) 1993-09-29 EP disclosed
US-5202344-A Disorders of the gastrointestinal, central nervous system and appetite regulatory systems G. D. SEARLE & CO. (US) 1993-04-13 US disclosed
WO-1992010476-A1 N-SUBSTITUTED LACTAMS USEFUL AS CHOLECYSTOKININ ANTAGONISTS G.D. SEARLE & CO. (US) 1992-06-25 WO disclosed