Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702504 | 0.83 | NPSR1 (0.47) | MAPTMAPK1POLBNPSR1NR1I2 | |
| SCHEMBL9448847 | 0.82 | MAPT (0.43) | MAPTMAPK1POLBNPSR1NR1I2 | |
| SCHEMBL915187 | 0.78 | FOLH1 (0.45) | MAPTMAPK1POLBNPSR1NR1I2 | |
| SCHEMBL12212067 | 0.77 | NPSR1 (0.42) | MAPTMAPK1POLBNPSR1NR1I2 | |
| SCHEMBL8671766 | 0.76 | MAPT (0.42) | KMT2AMAPTMAPK1POLBNPSR1 | |
| SCHEMBL9197005 | 0.76 | KMT2A (0.60) | KMT2APOLB | |
| SCHEMBL339745 | 0.76 | TSHR (0.54) | KMT2AMAPTMAPK1POLBNPSR1 | |
| SCHEMBL9445932 | 0.76 | NPSR1 (0.41) | MAPTMAPK1POLBNPSR1NR1I2 | |
| SCHEMBL9849219 | 0.76 | NPSR1 (0.41) | MAPTMAPK1POLBNPSR1NR1I2 | |
| SCHEMBL31733655 | 0.75 | MAPT (0.51) | KMT2AMAPTMAPK1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364996-A2 | Phosphono-hydroisoquinoline compounds useful in reducing neurotoxic injury | G.D. Searle & Co. (US) | 1990-04-25 | — | — | EP | disclosed |