SCHEMBL10348809

SCHEMBL10348809

CCCCCc1cccc(OP(O)Oc2cccc(CCCCC)c2CCCCC)c1CCCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.53
ALOX5 P09917 1/20 0.53
PPARA Q07869 3/20 0.47
LTB4R Q15722 1/20 0.45
LTB4R2 Q9NPC1 1/20 0.45
PPARG P37231 2/20 0.45
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
LIPG Q9Y5X9 1/20 0.42
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
SAE1 Q9UBE0 1/20 0.40
CYSLTR2 Q9NS75 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14686026 0.98 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL28621008 0.95 ALOX5 (0.46) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL9325512 0.94 THRA (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL11309656 0.93 THRA (0.50) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL160366 0.91 PTGS2 (0.53) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL271593 0.89 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL9339452 0.89 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL14352393 0.89 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL11127206 0.89 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL465412 0.89 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0285608-B1 WATER-IN-OIL EMULSIONS The Lubrizol Corporation (US) 1990-08-01 EP disclosed
EP-0364511-A1 WATER-IN-OIL EMULSIONS The Lubrizol Corporation (US) 1990-04-25 EP disclosed
US-4846985-A HYDROXYSULFIDE OR SECONDARY AMINE COMPOUND THE LUBRIZOL CORPORATION (US) 1989-07-11 US disclosed
US-4844756-A SALT DERIVED FROM HYDROCARBYL-SUBSTITUTED CARBOXYLIC ACID OR ANHYDRIDE OR DERIVATIVE, AND AMMONIA, AN AMINE, OR ALKALI OR ALKALINE EARTH METAL THE LUBRIZOL CORPORATION (US) 1989-07-04 US disclosed
WO-1989005848-A1 WATER-IN-OIL EMULSIONS THE LUBRIZOL CORPORATION (US) 1989-06-29 WO disclosed
EP-0285608-A1 WATER-IN-OIL EMULSIONS. LUBRIZOL CORP (US) 1988-10-12 EP disclosed
US-4708753-A NITROGEN CONTAINING SALT EMULSIFIERS; HYDRAULIC FLUIDS, EXPLOSIVES, ACIDIZING FLUIDS THE LUBRIZOL CORPORATION (US) 1987-11-24 US disclosed
WO-1987003613-A2 WATER-IN-OIL EMULSIONS THE LUBRIZOL CORPORATION (US) 1987-06-18 WO disclosed