Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325512 | 0.99 | THRA (0.51) | THRATHRBLTB4RLTB4R2PTGS2 | |
| SCHEMBL14686026 | 0.94 | PTGS2 (0.51) | THRATHRBLTB4RLTB4R2PTGS2 | |
| SCHEMBL10348809 | 0.93 | PTGS2 (0.53) | THRATHRBLTB4RLTB4R2PTGS2 | |
| SCHEMBL28621008 | 0.92 | ALOX5 (0.46) | THRATHRBLTB4RLTB4R2PTGS2 | |
| SCHEMBL29778064 | 0.90 | THRA (0.58) | THRATHRBLTB4RLTB4R2PTGS2 | |
| SCHEMBL8372832 | 0.90 | THRA (0.58) | THRATHRBLTB4RLTB4R2PTGS2 | |
| SCHEMBL28376630 | 0.90 | THRA (0.58) | THRATHRBLTB4RLTB4R2PTGS2 | |
| SCHEMBL317708 | 0.90 | THRA (0.58) | THRATHRBLTB4RLTB4R2PTGS2 | |
| SCHEMBL8433693 | 0.90 | THRA (0.58) | THRATHRBLTB4RLTB4R2PTGS2 | |
| SCHEMBL2350501 | 0.89 | THRA (0.51) | THRATHRBLTB4RLTB4R2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016392-B1 | CATALYST, ITS PREPARATION AND PROCESS FOR POLYMERIZING BUTADIENE | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |
| EP-0016392-A1 | Catalyst, its preparation and process for polymerizing butadiene | BAYER AG (DE) | 1980-10-01 | — | — | EP | disclosed |