Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NQO1 | P15559 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | VKORC1 | Q9BQB6 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522178 | 0.87 | ALDH1A1 (0.50) | ALDH1A1NQO1LMNAMEN1KMT2A | |
| Zinc Ion SCHEMBL29660558 | 0.84 | ALDH1A1 (0.48) | ALDH1A1NQO1LMNAMEN1KMT2A | |
| SCHEMBL2028247 | 0.81 | ALDH1A1 (0.50) | ALDH1A1NQO1LMNAMEN1KMT2A | |
| SCHEMBL10710132 | 0.76 | CA12 (0.49) | ALDH1A1NQO1LMNAMEN1KMT2A | |
| SCHEMBL28455189 | 0.73 | ALDH1A1 (0.47) | ALDH1A1NQO1LMNAMEN1KMT2A | |
| SCHEMBL28719517 | 0.73 | NQO1 (0.55) | ALDH1A1NQO1LMNAMEN1KMT2A | |
| SCHEMBL1568301 | 0.71 | NQO1 (0.66) | ALDH1A1NQO1LMNAMEN1KMT2A | |
| SCHEMBL14169915 | 0.70 | NQO1 (0.75) | ALDH1A1NQO1LMNAMEN1KMT2A | |
| SCHEMBL3931144 | 0.70 | GAA (0.57) | ALDH1A1NQO1LMNAMEN1KMT2A | |
| SCHEMBL10638322 | 0.69 | NQO1 (0.73) | ALDH1A1NQO1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277139-B1 | 7-AMINO-4-METHYL-COUMARIN-3-CARBOXYALKYL DERIVATIVES AND FLUORESCENT CONJUGATES THEREOF | BIOCARB AB (SE) | 1990-08-08 | — | — | EP | disclosed |