SCHEMBL28455189

SCHEMBL28455189

NCc1c(CCBr)c2ccccc2oc1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
LMNA P02545 4/20 0.47
NQO1 P15559 3/20 0.47
TP53 P04637 2/20 0.47
TSHR P16473 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP3A4 P08684 2/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
ABCB11 O95342 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
PDE4D Q08499 1/20 0.47
PCSK7 Q16549 1/20 0.47
GPR35 Q9HC97 1/20 0.47
KDM4E B2RXH2 6/20 0.45
GAA P10253 5/20 0.45
VKORC1 Q9BQB6 2/20 0.43
MAPT P10636 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18154540 0.77 ALDH1A1 (0.46) ALDH1A1LMNANQO1TP53TSHR
SCHEMBL2028247 0.77 ALDH1A1 (0.50) ALDH1A1LMNANQO1TP53TSHR
SCHEMBL26837593 0.74 PLK1 (0.40) ALDH1A1LMNANQO1TP53TSHR
SCHEMBL2522178 0.74 ALDH1A1 (0.50) ALDH1A1LMNANQO1TP53TSHR
SCHEMBL27594102 0.74 MAOA (0.50) ALDH1A1LMNANQO1TP53TSHR
SCHEMBL27687468 0.73 NQO1 (0.53) ALDH1A1LMNANQO1TP53TSHR
SCHEMBL10349945 0.73 ALDH1A1 (0.49) ALDH1A1LMNANQO1TP53TSHR
SCHEMBL27699860 0.73 NPC1 (0.48) ALDH1A1LMNANQO1TP53TSHR
SCHEMBL10710132 0.72 CA12 (0.49) ALDH1A1LMNANQO1TP53TSHR
Zinc Ion SCHEMBL29660558 0.72 ALDH1A1 (0.48) ALDH1A1LMNANQO1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108079294-B Ferrocene-lanthanide metal compound and preparation method and application thereof 南京工业大学 2020-10-02 CN disclosed