SCHEMBL1035008

SCHEMBL1035008

CC#Cc1cc(C=O)n([C@H]2CC[C@@H](COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HSP90AA1 P07900 1/20 0.30
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1032736 0.83 TYMP (0.48) TYMP
SCHEMBL12768228 0.79
SCHEMBL1034976 0.78 ALDH1A1 (0.36)
SCHEMBL6323257 0.69 MEN1 (0.35) MEN1KMT2AHSP90AA1TYMP
SCHEMBL9219565 0.68 DUT (0.48) HSP90AA1TYMP
SCHEMBL15827264 0.65 BCHE (0.48) HSP90AA1
SCHEMBL5055957 0.65 BCHE (0.48) HSP90AA1
SCHEMBL1697175 0.65 BCHE (0.48) HSP90AA1
SCHEMBL24393850 0.65 HSP90AA1 (0.40) HSP90AA1TYMP
SCHEMBL9128931 0.65 TYMP (0.36) MEN1KMT2ATYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2275538-B1 NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY TAGCYX BIOTECHNOLOGIES (JP) 2016-10-05 EP disclosed
US-8426569-B2 DNA capable of being amplified by PCR with high selectivity and high efficiency RIKEN (JP) 2013-04-23 US disclosed
US-20110053782-A1 NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY RIKEN (JP) 2011-03-03 US disclosed
EP-2275538-A1 NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY Riken (JP) 2011-01-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110053782-A1 NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY POLRMT, POLN, POLL MEN1 4357/4885KMT2A 1838/4885HSP90AA1 2954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.