Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | TK2 | O00142 | 7/20 | 0.45 |
| ▸ | TK1 | P04183 | 7/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15827264 | 1.00 | BCHE (0.48) | BCHETK2TK1HSP90AA1 | |
| SCHEMBL5055957 | 1.00 | BCHE (0.48) | BCHETK2TK1HSP90AA1 | |
| SCHEMBL10292697 | 0.91 | TK1 (0.43) | BCHETK2TK1HSP90AA1 | |
| SCHEMBL24393850 | 0.89 | HSP90AA1 (0.40) | BCHETK2TK1HSP90AA1 | |
| SCHEMBL13283250 | 0.89 | HSP90AA1 (0.40) | BCHETK2TK1HSP90AA1 | |
| SCHEMBL25764371 | 0.89 | TK2 (0.44) | TK2TK1HSP90AA1 | |
| SCHEMBL13493930 | 0.86 | DUT (0.42) | BCHEHSP90AA1 | |
| SCHEMBL5835187 | 0.86 | HSP90AA1 (0.38) | BCHETK2TK1HSP90AA1 | |
| SCHEMBL21625674 | 0.85 | HSP90AA1 (0.47) | TK2TK1HSP90AA1 | |
| SCHEMBL22983984 | 0.85 | HSP90AA1 (0.47) | TK2TK1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305954-A1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2017-10-26 | — | — | US | claimed |
| EP-2576577-B1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | LIFE TECHNOLOGIES CORP (US) | 2015-03-18 | — | — | EP | claimed |
| US-8658776-B2 | Synthesis of 2′,3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2014-02-25 | — | — | US | claimed |
| US-20110294122-A1 | Synthesis of 2', 3'-Dideoxynucleosides for Automated DNA Synthesis and Pyrophosphorolysis Activated Polymerization | Life Technologies Corporation (US) | 2011-12-01 | — | — | US | claimed |
| WO-2023247966-A1 | CYCLOADDITION REACTIONS | UNIVERSITY OF STRATHCLYDE (GB) | 2023-12-28 | — | — | WO | disclosed |
| EP-2813512-B1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |
| WO-2019200273-A1 | NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-10-17 | — | — | WO | disclosed |
| US-20170305954-A1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2017-10-26 | — | — | US | disclosed |
| US-9732112-B2 | Synthesis of 2′,3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2017-08-15 | — | — | US | disclosed |
| US-20160108079-A1 | Synthesis Of 2',3'-Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization | Life Technologies Corporation | 2016-04-21 | — | — | US | disclosed |
| US-9228227-B2 | Synthesis of 2′, 3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2016-01-05 | — | — | US | disclosed |
| EP-2576577-B1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | LIFE TECHNOLOGIES CORP (US) | 2015-03-18 | — | — | EP | disclosed |
| US-20150045547-A1 | Synthesis Of 2' , 3' -Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization | Life Technologies Corporation (US) | 2015-02-12 | — | — | US | disclosed |
| US-8658776-B2 | Synthesis of 2′,3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2014-02-25 | — | — | US | disclosed |
| EP-2576577-A2 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011150277-A2 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2011-12-01 | — | — | WO | disclosed |
| US-20110294122-A1 | Synthesis of 2', 3'-Dideoxynucleosides for Automated DNA Synthesis and Pyrophosphorolysis Activated Polymerization | Life Technologies Corporation (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110118455-A1 | PROTECTING GROUP FOR INDOLE GROUP, NUCLEIC ACID-SYNTHESIZING AMIDITE AND NUCLEIC ACID-SYNTHESIZING METHOD | FUJITSU LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20110118455-A1 | PROTECTING GROUP FOR INDOLE GROUP, NUCLEIC ACID-SYNTHESIZING AMIDITE AND NUCLEIC ACID-SYNTHESIZING METHOD | FUJITSU LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305954-A1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | DCTD, MTAP, RNGTT | BCHE 2047/4885TK2 116/4885TK1 102/4885 |
| US-20110118455-A1 | PROTECTING GROUP FOR INDOLE GROUP, NUCLEIC ACID-SYNTHESIZING AMIDITE AND NUCLEIC ACID-SYNTHESIZING METHOD | INMT, NSUN2, RNMT | BCHE 1286/4885TK2 2220/4885TK1 1451/4885 |
| US-20160108079-A1 | Synthesis Of 2',3'-Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization | DCTD, MTAP, RNGTT | BCHE 2047/4885TK2 116/4885TK1 102/4885 |
| US-20110294122-A1 | Synthesis of 2', 3'-Dideoxynucleosides for Automated DNA Synthesis and Pyrophosphorolysis Activated Polymerization | DCTD, MTAP, RNGTT | BCHE 2047/4885TK2 116/4885TK1 102/4885 |
| US-20150045547-A1 | Synthesis Of 2' , 3' -Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization | DCTD, MTAP, RNGTT | BCHE 2047/4885TK2 116/4885TK1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.