SCHEMBL10350353

SCHEMBL10350353

CC(C)(C)c1cc(C(C)(C)C)c(C(=O)c2ccccc2)c(C(C)(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
PTGS2 P35354 2/20 0.48
RXRA P19793 2/20 0.47
RXRB P28702 2/20 0.47
SRD5A2 P31213 1/20 0.47
ALDH1A1 P00352 1/20 0.46
TDP1 Q9NUW8 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 2/20 0.45
KCNK9 Q9NPC2 1/20 0.45
MAPT P10636 1/20 0.45
PTGS1 P23219 1/20 0.44
NPC1 O15118 1/20 0.44
HSP90AA1 P07900 1/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
RXRG P48443 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2921671 0.85 ALDH1A1 (0.46) ALOX5PTGS2ALDH1A1TDP1L3MBTL1
SCHEMBL28557290 0.85 ALDH1A1 (0.46) ALOX5PTGS2SRD5A2ALDH1A1TDP1
SCHEMBL11792121 0.83 LMNA (0.49) RXRARXRBSRD5A2ALDH1A1TDP1
SCHEMBL8713885 0.82 ALDH1A1 (0.52) ALOX5PTGS2SRD5A2ALDH1A1TDP1
SCHEMBL15685928 0.81 TDP1 (0.59) ALOX5PTGS2RXRARXRBSRD5A2
SCHEMBL27510569 0.81 ALDH1A1 (0.56) ALOX5PTGS2RXRARXRBSRD5A2
SCHEMBL547814 0.80 ALDH1A1 (0.45) SRD5A2ALDH1A1TDP1L3MBTL1ATM
SCHEMBL6466602 0.78 GLRA3 (0.57) ALOX5PTGS2RXRARXRBSRD5A2
SCHEMBL7189213 0.77 ALOX5 (0.38) ALOX5PTGS2RXRARXRBTDP1
SCHEMBL29027526 0.76 TDP1 (0.53) RXRARXRBSRD5A2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0209831-B1 SUBSTITUTED BENZOPHENONES AND THEIR LIQUID MIXTURES SUITABLE FOR USE AS PHOTOPOLYMERISATION INITIATORS FRATELLI LAMBERTI S.p.A. (IT) 1990-05-16 EP disclosed
US-4755541-A Substituted benzophenones and their liquid mixtures suitable for use as photopolymerization initiators FRATELLI LAMBERTI SPA (IT) 1988-07-05 US disclosed
EP-0209831-A2 Substituted benzophenones and their liquid mixtures suitable for use as photopolymerisation initiators FRATELLI LAMBERTI S.p.A. (IT) 1987-01-28 EP disclosed