Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSPA5 | P11021 | 4/20 | 0.53 |
| ▸ | HSPA9 | P38646 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethylbenzene SCHEMBL10350569 | 0.80 | MEN1 (0.65) | LMNATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL10351392 | 0.79 | NPC1 (0.48) | LMNATSHRHSPA5NPC1RAB9A | |
| SCHEMBL20887927 | 0.78 | LMNA (0.75) | LMNATSHRHSPA5HSPA9HSD17B10 | |
| SCHEMBL12241949 | 0.75 | SCN9A (0.50) | LMNATSHRFFAR2HTT | |
| SCHEMBL2900950 | 0.74 | NR3C1 (0.82) | NR3C1PGRAR | |
| SCHEMBL667096 | 0.72 | NR3C1 (0.65) | LMNATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL1107000 | 0.72 | ADORA2A (0.68) | LMNATSHRHSPA5HSPA9HSD17B10 | |
| SCHEMBL12647710 | 0.71 | LMNA (0.64) | LMNATSHRHSPA5HSPA9HSD17B10 | |
| SCHEMBL12264158 | 0.71 | ALDH1A1 (0.49) | LMNATSHRHSD17B10NPC1RAB9A | |
| SCHEMBL2893740 | 0.70 | NR3C1 (0.62) | LMNATSHRNPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141713-B1 | Process for preparation of 2-substituted quinoline-3- carboxamides | ROUSSEL-UCLAF (FR) | 1990-05-30 | — | — | EP | disclosed |