Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.39 |
| ▸ | PGK2 | P07205 | 3/20 | 0.39 |
| ▸ | ACP3 | P15309 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585204 | 0.88 | TSHR (0.41) | PGK1PGK2ACP3TSHRMEN1 | |
| SCHEMBL6703082 | 0.83 | TSHR (0.38) | PGK1PGK2ACP3TSHRMEN1 | |
| SCHEMBL2034011 | 0.80 | FDPS (0.45) | ACP3TSHRMEN1ALDH1A1GAA | |
| SCHEMBL29024532 | 0.80 | ACP3 (0.41) | PGK1PGK2ACP3GAAKMT2A | |
| SCHEMBL11762883 | 0.79 | ACP3 (0.48) | PGK1PGK2ACP3TSHRMEN1 | |
| SCHEMBL9445937 | 0.77 | FDPS (0.36) | ACP3TSHRMEN1ALDH1A1GAA | |
| SCHEMBL3346090 | 0.77 | ACP3 (0.61) | PGK1PGK2ACP3MEN1KMT2A | |
| SCHEMBL28514766 | 0.77 | PTPN5 (0.40) | ACP3TSHRMEN1ALDH1A1GAA | |
| SCHEMBL8935935 | 0.76 | PTPN5 (0.42) | ACP3TSHRMEN1ALDH1A1GAA | |
| SCHEMBL11763736 | 0.76 | PGK1 (0.42) | PGK1PGK2TSHRMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276723-B1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-01-27 | — | — | EP | disclosed |
| EP-2276723-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009141026-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH, (DE) | 2009-11-26 | — | — | WO | disclosed |