Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.36 |
| ▸ | ACP3 | P15309 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585204 | 0.84 | TSHR (0.41) | FDPSACP3TSHRALDH1A1MEN1 | |
| SCHEMBL6703082 | 0.79 | TSHR (0.38) | FDPSACP3TSHRALDH1A1MEN1 | |
| SCHEMBL10348803 | 0.78 | KMT2A (0.44) | TSHRALDH1A1MEN1GAAPKM | |
| SCHEMBL1035151 | 0.77 | PGK1 (0.39) | FDPSACP3GABRA1GABRB2TSHR | |
| SCHEMBL7194498 | 0.77 | PTPN1 (0.47) | PTPN5PTPN1 | |
| SCHEMBL3890478 | 0.77 | GABRA1 (0.42) | FDPSACP3GABRA1GABRB2TSHR | |
| SCHEMBL29024532 | 0.76 | ACP3 (0.41) | ACP3GAAKMT2APTPN5PTPN1 | |
| SCHEMBL2034011 | 0.76 | FDPS (0.45) | FDPSACP3TSHRALDH1A1MEN1 | |
| SCHEMBL11762883 | 0.75 | ACP3 (0.48) | FDPSACP3GABRA1GABRB2TSHR | |
| SCHEMBL3346090 | 0.73 | ACP3 (0.61) | ACP3MEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |
| EP-0242709-A2 | Antagonists of specific excitatory amino acid neurotransmitter receptors | NOVA PHARMACEUTICAL CORPORATION (US) | 1987-10-28 | — | — | EP | disclosed |
| WO-1987006131-A1 | ANTAGONISTS OF SPECIFIC EXCITATORY AMINO ACID NEUROTRANSMITTER RECEPTORS | RZESZOTARSKI JANUSZ WACLAW (US) | 1987-10-22 | — | — | WO | disclosed |
| US-4657899-A | ANALGESICS, COGNITION ACTIVATORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1987-04-14 | — | — | US | disclosed |