Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585204 | 0.82 | TSHR (0.41) | PTPN5TSHRALDH1A1GAAACP3 | |
| SCHEMBL6886173 | 0.82 | IMPDH2 (0.40) | PTPN5ARACP3 | |
| SCHEMBL11895632 | 0.81 | AR (0.35) | PTPN5ARALDH1A1KDM4E | |
| SCHEMBL11499398 | 0.80 | PTPN5 (0.40) | PTPN5TSHRARALDH1A1GAA | |
| SCHEMBL5033925 | 0.78 | PTPN5 (0.45) | PTPN5NAMPTTSHRARALDH1A1 | |
| SCHEMBL6703082 | 0.78 | TSHR (0.38) | PTPN5TSHRALDH1A1GAAACP3 | |
| SCHEMBL11235850 | 0.77 | PTPN5 (0.40) | PTPN5NAMPTTSHRARALDH1A1 | |
| SCHEMBL1035151 | 0.76 | PGK1 (0.39) | TSHRALDH1A1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL9603131 | 0.76 | PLCG1 (0.50) | — | |
| SCHEMBL29024532 | 0.75 | ACP3 (0.41) | PTPN5GAAMAPK1KDM4EACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565191-A | SUNSCREEN AGENTS | 3V INC. (US) | 1996-10-15 | — | — | US | disclosed |
| US-5446051-A | Nervous system disorder and brain disorder | ELI LILLY AND COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| EP-0658341-A1 | Cosmetic and dermatological compositions for the protection against UV radiation containing stilbene derivatives | 3V SIGMA S.p.A (IT) | 1995-06-21 | — | — | EP | disclosed |
| US-5152922-A | 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-5072016-A | MIXTURES OF FLUORESCENT WHITENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0252009-B1 | 1,4-DISTYRYL BENZENE COMPOUNDS AND THEIR MIXTURES WITH OTHER 1,4-DISTYRYL BENZENE COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-08-01 | — | — | EP | disclosed |
| US-4891153-A | Mixtures of fluorescent whitening agents | CIBA-GEIGY CORPORATION (US) | 1990-01-02 | — | — | US | disclosed |
| US-4867906-A | Mixtures of fluorescent whitening agents | CIBA-GEIGY CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |
| US-4778622-A | Mixtures of fluorescent whitening agents | CIBA-GEIGY CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0238446-A1 | Mixtures of optical brighteners | CIBA-GEIGY AG (CH) | 1987-09-23 | — | — | EP | disclosed |
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |
| EP-0019172-A1 | 6-Substituted 11-alkylene-morphantridines, process for preparing them and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1980-11-26 | — | — | EP | disclosed |
| US-4223035-A | ANTIDEPRESSANT, ANTICHOLINERGIC, HORMONE INHIBITOR | SANDOZ LTD. (CH) | 1980-09-16 | — | — | US | disclosed |
| US-4167628-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1979-09-11 | — | — | US | disclosed |