Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28266853 | 0.89 | GAA (0.48) | ALDH1A1HTTSMN1; SMN2HPGDRECQL | |
| SCHEMBL13476245 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HTTSMN1; SMN2HPGDIDO1 | |
| SCHEMBL450781 | 0.80 | ALDH1A1 (0.77) | ALDH1A1HTTSMN1; SMN2HPGDRECQL | |
| SCHEMBL10351595 | 0.80 | L3MBTL1 (0.53) | ALDH1A1HTTSMN1; SMN2HPGDGAA | |
| SCHEMBL21611657 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2HPGDGAA | |
| SCHEMBL28051115 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HTTSMN1; SMN2HPGDGAA | |
| SCHEMBL10351592 | 0.78 | GAA (0.64) | ALDH1A1HTTSMN1; SMN2HPGDGAA | |
| SCHEMBL27937115 | 0.78 | ERN1 (0.59) | ALDH1A1HTTSMN1; SMN2HPGDIDO1 | |
| SCHEMBL28765646 | 0.78 | L3MBTL1 (0.71) | ALDH1A1HTTSMN1; SMN2HPGDIDO1 | |
| SCHEMBL14848863 | 0.77 | GAA (0.58) | ALDH1A1HTTSMN1; SMN2HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210140-B1 | INHIBITORS OF BENZYLAMINOXIDASES, SELECTIVE WITH RESPECT TO OTHER AMINOXIDASES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1990-06-13 | — | — | EP | disclosed |
| US-4888283-A | Selective inhibitors of benzylaminoxidases with respect to other aminoxidases | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1989-12-19 | — | — | US | disclosed |
| EP-0210140-A2 | Inhibitors of benzylaminoxidases, selective with respect to other aminoxidases | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1987-01-28 | — | — | EP | disclosed |