Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15349839 | 0.90 | LMNA (0.47) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL13996312 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL3218241 | 0.82 | PTPN1 (0.42) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10351595 | 0.82 | L3MBTL1 (0.53) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL19585326 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL1665307 | 0.81 | ALDH1A1 (0.81) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10351592 | 0.81 | GAA (0.64) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL6540995 | 0.80 | GAA (0.48) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10612658 | 0.80 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL489248 | 0.80 | PPARA (0.47) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103635460-B | Be used for the treatment of addicted compound | GILEAD SCIENCES, INC. (US) | 2016-03-16 | — | — | CN | disclosed |