SCHEMBL450781

SCHEMBL450781

O=Cc1ccccc1OCCO

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.77
HTT P42858 2/20 0.77
SMN1; SMN2 Q16637 2/20 0.77
HPGD P15428 1/20 0.77
PTGDR2 Q9Y5Y4 1/20 0.62
SRC P12931 2/20 0.52
MAPT P10636 1/20 0.51
KMT2A Q03164 5/20 0.50
LMNA P02545 3/20 0.50
GAA P10253 1/20 0.50
MEN1 O00255 3/20 0.49
RAD52 P43351 1/20 0.48
RECQL P46063 2/20 0.47
TDP1 Q9NUW8 2/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
IDO1 P14902 1/20 0.46
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7987554 0.90 ALDH1A1 (0.74) ALDH1A1HTTSMN1; SMN2HPGDPTGDR2
SCHEMBL7399599 0.89 ALDH1A1 (0.72) ALDH1A1HTTSMN1; SMN2HPGDPTGDR2
SCHEMBL29771355 0.89 ALDH1A1 (0.72) ALDH1A1HTTSMN1; SMN2HPGDPTGDR2
SCHEMBL11685370 0.89 ALDH1A1 (0.72) ALDH1A1HTTSMN1; SMN2HPGDPTGDR2
SCHEMBL25375219 0.89 ALDH1A1 (0.71) ALDH1A1HTTSMN1; SMN2HPGDPTGDR2
SCHEMBL6914412 0.87 ALDH1A1 (1.00) ALDH1A1HTTSMN1; SMN2HPGDPTGDR2
SCHEMBL28673681 0.87 ALDH1A1 (0.69) ALDH1A1HTTSMN1; SMN2HPGDPTGDR2
SCHEMBL28684089 0.87 ALDH1A1 (0.69) ALDH1A1HTTSMN1; SMN2HPGDPTGDR2
SCHEMBL27717487 0.87 ALDH1A1 (0.69) ALDH1A1HTTSMN1; SMN2HPGDPTGDR2
SCHEMBL7363888 0.87 ALDH1A1 (0.69) ALDH1A1HTTSMN1; SMN2HPGDPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119571637-B Waterborne polyurethane-based flame-retardant microfiber synthetic leather and preparation method thereof 浙江梅盛新材料有限公司 2025-05-02 CN claimed
CN-119571637-A Waterborne polyurethane-based flame-retardant microfiber synthetic leather and preparation method thereof 浙江梅盛新材料有限公司 2025-03-07 CN claimed
CN-112731766-B Hard mask composition, hard mask layer and method of forming pattern 三星SDI株式会社 2024-12-17 CN claimed
CN-115160752-B Polylactic acid composite material for mulching film and application thereof 山西生物质新材料产业研究院有限公司 2023-08-01 CN claimed
CN-115160752-A Polylactic acid composite material for mulching film and application thereof 山西生物质新材料产业研究院有限公司 2022-10-11 CN claimed
CN-112731766-A Hardmask composition, hardmask layer and method of forming pattern 三星SDI株式会社 2021-04-30 CN claimed
US-20210109449-A1 HARDMASK COMPOSITION, HARDMASK LAYER AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2021-04-15 US claimed
CN-108625220-B Fire retardant for wood paper 浙江鸿浩科技有限公司 2021-03-23 CN claimed
CN-109516933-B Preparation method of silodosin intermediate 安徽省庆云医药股份有限公司 2021-03-02 CN claimed
CN-108642962-B High-temperature-resistant halogen-free paper flame retardant 浙江鸿浩科技有限公司 2020-11-24 CN claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
EP-4731691-A1 CURABLE COMPOSITION HAVING AN ALDEHYDE-FUNCTIONAL POLYMER Sika Technology AG (CH) 2026-04-29 EP disclosed
US-20260098021-A1 Nitrosation Reagents and Methods UNIV CALIFORNIA (US) 2026-04-09 US disclosed
US-5049634-A Derivatized and/or crosslinked products from acetal- and aldehyde-containing polysaccharide graft polymers NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1991-09-17 US disclosed
EP-0418917-A2 Monomers and polymers containing acetal and aldehyde groups National Starch and Chemical Investment Holding Corporation (US) 1991-03-27 EP disclosed
US-4053415-A UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098021-A1 Nitrosation Reagents and Methods TXN, CBR1, CBR3 ALDH1A1 716/4885HTT 1114/4885SMN1; SMN2 1335/4885
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 ALDH1A1 83/4885HTT 3885/4885SMN1; SMN2 3654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.