Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352221 | 0.92 | AR (0.36) | ARFFAR4ALDH1A1HPGDKDM4E | |
| SCHEMBL10352424 | 0.88 | AR (0.36) | AR | |
| SCHEMBL10352216 | 0.82 | AR (0.34) | ARALDH1A1 | |
| SCHEMBL10352426 | 0.81 | KDR (0.34) | AR | |
| SCHEMBL10352218 | 0.81 | AR (0.34) | AR | |
| SCHEMBL10352215 | 0.79 | CYP19A1 (0.47) | ARFFAR4ALDH1A1HPGDF2 | |
| SCHEMBL10353036 | 0.78 | LMNA (0.41) | ARALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL10352797 | 0.69 | MAOB (0.33) | ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL10352210 | 0.68 | ALDH1A1 (0.56) | ARALDH1A1HPGDKDM4EF2 | |
| SCHEMBL10353035 | 0.66 | CYP19A1 (0.56) | ARALDH1A1HPGDKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222403-B2 | Heteroaromatic phthalonitriles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2012-07-17 | — | — | US | disclosed |
| US-20110108755-A1 | HETEROAROMATIC PHTHALONITRILES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110108755-A1 | HETEROAROMATIC PHTHALONITRILES | ARNT, PBRM1, NR4A1 | AR 14/4885FFAR4 4346/4885ALDH1A1 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.