SCHEMBL103526

SCHEMBL103526

C=Cc1ccc(-c2ccc(C(OO)c3ccc(C=C)cc3F)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35
PTGS2 P35354 2/20 0.35
ALDH1A1 P00352 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103183 0.91 APP (0.34) IDO1TDO2PTGS2
SCHEMBL103695 0.83 APP (0.36) PTGS2
SCHEMBL103180 0.83 PTGS2 (0.38) IDO1TDO2PTGS2ALDH1A1TRPA1
SCHEMBL102855 0.81 ALDH1A1 (0.44) PTGS2ALDH1A1TRPA1
SCHEMBL17897413 0.76 ALDH1A1 (0.50) IDO1TDO2PTGS2ALDH1A1TRPA1
SCHEMBL20045121 0.75 PTGS2 (0.32) PTGS2
SCHEMBL17084289 0.73 TYR (0.36)
SCHEMBL103531 0.70 PTGS2 (0.35) PTGS2ALDH1A1
SCHEMBL20267008 0.69 ALDH1A1 (0.40) ALDH1A1TRPA1
SCHEMBL17445753 0.68 ALDH1A1 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011773-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-07-03 US disclosed
US-20180100105-A1 ANISOTROPIC SCATTERING FILM DIC CORPORATION (JP) 2018-04-12 US disclosed
US-9828548-B2 Liquid-crystal composition DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9809752-B2 Liquid crystal display device DIC CORPORATION (JP) 2017-11-07 US disclosed
US-9771517-B2 Liquid-crystal optical modulation element DIC CORPORATION (JP) 2017-09-26 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160194561-A1 DIFLUOROPHENYL LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2016-07-07 US disclosed
US-20160130502-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-05-12 US disclosed
US-20160017226-A1 LIQUID-CRYSTAL OPTICAL MODULATION ELEMENT DIC CORPORATION (JP) 2016-01-21 US disclosed
US-20150259600-A1 LIQUID-CRYSTAL COMPOSITION DIC CORPORATION (JP) 2015-09-17 US disclosed
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
US-20140327862-A1 FERROELECTRIC LIQUID CRYSTAL COMPOSITION AND FERROELECTRIC LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2014-11-06 US disclosed
US-20140313468-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2014-10-23 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed