SCHEMBL102855

SCHEMBL102855

C=Cc1ccc(-c2ccc(C(OO)c3ccc(C=C)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
PTGS2 P35354 2/20 0.37
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 1/20 0.34
HDAC2 Q92769 1/20 0.34
DAPK3 O43293 1/20 0.32
JAK2 O60674 1/20 0.32
ABL1 P00519 1/20 0.32
NTRK1 P04629 1/20 0.32
FYN P06241 1/20 0.32
CSF1R P07333 1/20 0.32
RET P07949 1/20 0.32
MET P08581 1/20 0.32
PDGFRB P09619 1/20 0.32
FGFR1 P11362 1/20 0.32
FLT3 P36888 1/20 0.32
MAPK8 P45983 1/20 0.32
GSK3B P49841 1/20 0.32
CDK9 P50750 1/20 0.32
RPS6KA3 P51812 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17897413 0.94 ALDH1A1 (0.50) ALDH1A1PTGS2TDP1TSHRTRPA1
SCHEMBL17445753 0.85 ALDH1A1 (0.41) ALDH1A1TDP1TSHR
SCHEMBL103531 0.83 PTGS2 (0.35) ALDH1A1PTGS2
SCHEMBL103526 0.81 IDO1 (0.35) ALDH1A1PTGS2TRPA1
SCHEMBL103695 0.81 APP (0.36) PTGS2TSHR
SCHEMBL103180 0.81 PTGS2 (0.38) ALDH1A1PTGS2TDP1TRPA1
SCHEMBL103315 0.80 CHRNB2 (0.41) ALDH1A1TDP1
SCHEMBL7518854 0.75 ALDH1A1 (0.48) ALDH1A1PTGS2TDP1TSHRHDAC2
SCHEMBL593791 0.75 ALDH1A1 (0.79) ALDH1A1PTGS2TDP1TSHRHDAC2
SCHEMBL583978 0.75 ALDH1A1 (0.79) ALDH1A1PTGS2TDP1TSHRHDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011773-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-07-03 US disclosed
US-20180100105-A1 ANISOTROPIC SCATTERING FILM DIC CORPORATION (JP) 2018-04-12 US disclosed
US-9828548-B2 Liquid-crystal composition DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9809752-B2 Liquid crystal display device DIC CORPORATION (JP) 2017-11-07 US disclosed
US-9771517-B2 Liquid-crystal optical modulation element DIC CORPORATION (JP) 2017-09-26 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160194561-A1 DIFLUOROPHENYL LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2016-07-07 US disclosed
US-20160130502-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-05-12 US disclosed
US-20160017226-A1 LIQUID-CRYSTAL OPTICAL MODULATION ELEMENT DIC CORPORATION (JP) 2016-01-21 US disclosed
US-20150259600-A1 LIQUID-CRYSTAL COMPOSITION DIC CORPORATION (JP) 2015-09-17 US disclosed
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
US-20140327862-A1 FERROELECTRIC LIQUID CRYSTAL COMPOSITION AND FERROELECTRIC LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2014-11-06 US disclosed
US-20140313468-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2014-10-23 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed