SCHEMBL103695

SCHEMBL103695

C=Cc1ccc(C(OO)c2ccc(-c3ccc(C=C)cc3F)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.36
CYP2C19 P33261 3/20 0.36
CYP2C9 P11712 2/20 0.35
CYP3A4 P08684 1/20 0.35
AKR1C3 P42330 5/20 0.35
AKR1C2 P52895 5/20 0.35
PTGS1 P23219 4/20 0.35
PTGS2 P35354 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
PSEN1 P49768 2/20 0.35
PSEN2 P49810 2/20 0.35
APH1B Q8WW43 2/20 0.35
NCSTN Q92542 2/20 0.35
APH1A Q96BI3 2/20 0.35
PSENEN Q9NZ42 2/20 0.35
FABP2 P12104 1/20 0.35
TSHR P16473 1/20 0.35
AKR1C4 P17516 1/20 0.35
ADRA2B P18089 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103183 0.91 APP (0.34) APPCYP2C19CYP2C9CYP3A4AKR1C3
SCHEMBL103526 0.83 IDO1 (0.35) PTGS2
SCHEMBL102855 0.81 ALDH1A1 (0.44) PTGS2TSHR
SCHEMBL104015 0.80 ALDH1A1 (0.42) APPCYP2C19CYP2C9CYP3A4TSHR
SCHEMBL17897413 0.79 ALDH1A1 (0.50) PTGS2TSHR
SCHEMBL27834100 0.77 PDE3B (0.40) CYP3A4ALOX5APFEN1
SCHEMBL15834804 0.74 ALDH1A1 (0.44) APPCYP2C19CYP2C9CYP3A4PTGS2
SCHEMBL1942123 0.73 TSHR (0.43) CYP2C19CYP2C9AKR1C3AKR1C2PTGS1
SCHEMBL11671603 0.73 PPARG (0.45) APPCYP2C19CYP2C9CYP3A4PTGS2
SCHEMBL18785322 0.72 NFE2L2 (0.37) CYP3A4LMNAMAPTMAOBALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011773-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-07-03 US disclosed
US-20180100105-A1 ANISOTROPIC SCATTERING FILM DIC CORPORATION (JP) 2018-04-12 US disclosed
US-9828548-B2 Liquid-crystal composition DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9809752-B2 Liquid crystal display device DIC CORPORATION (JP) 2017-11-07 US disclosed
US-9771517-B2 Liquid-crystal optical modulation element DIC CORPORATION (JP) 2017-09-26 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160194561-A1 DIFLUOROPHENYL LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2016-07-07 US disclosed
US-20160130502-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-05-12 US disclosed
US-20160017226-A1 LIQUID-CRYSTAL OPTICAL MODULATION ELEMENT DIC CORPORATION (JP) 2016-01-21 US disclosed
US-20150259600-A1 LIQUID-CRYSTAL COMPOSITION DIC CORPORATION (JP) 2015-09-17 US disclosed
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
US-20140327862-A1 FERROELECTRIC LIQUID CRYSTAL COMPOSITION AND FERROELECTRIC LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2014-11-06 US disclosed
US-20140313468-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2014-10-23 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed