Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.64 |
| ▸ | AR | P10275 | 3/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500255 | 0.93 | CYP3A4 (0.63) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL10352327 | 0.92 | NR3C1 (0.74) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL10543449 | 0.92 | NR3C1 (0.74) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL10352704 | 0.92 | NR3C1 (0.74) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL7081817 | 0.86 | NR3C1 (0.70) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL8674574 | 0.86 | NR3C1 (0.70) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL8501453 | 0.86 | NR3C1 (0.55) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL7741861 | 0.84 | LMNA (0.64) | NR3C1PGRCYP3A4USP2HSD17B10 | |
| SCHEMBL7894324 | 0.81 | NR3C1 (0.68) | NR3C1ARPGRCYP3A4USP2 | |
| SCHEMBL8138913 | 0.80 | NR3C1 (0.66) | NR3C1ARPGRCYP3A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675897-A1 | NEW STEROIDS. | RHONE POULENC RORER LTD (GB) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994014834-A1 | NEW STEROIDS | RHONE-POULENC RORER LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |