Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 13/20 | 0.79 |
| ▸ | HSD17B2 | P37059 | 13/20 | 0.79 |
| ▸ | FASN | P49327 | 1/20 | 0.61 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.59 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.59 |
| ▸ | CLK1 | P49759 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31621156 | 0.87 | HTT (0.61) | HSD17B1HSD17B2DYRK1ADYRK1BHTT | |
| SCHEMBL1758239 | 0.87 | HTT (0.61) | HSD17B1HSD17B2DYRK1ADYRK1BHTT | |
| SCHEMBL15851049 | 0.86 | HSD17B1 (0.60) | HSD17B1HSD17B2HTTSMN1; SMN2NPC1 | |
| SCHEMBL5962849 | 0.85 | HSD17B1 (0.64) | HSD17B1HSD17B2HTTSMN1; SMN2NPC1 | |
| SCHEMBL11053174 | 0.85 | HTT (0.64) | HSD17B1HSD17B2DYRK1ADYRK1BHTT | |
| SCHEMBL9752049 | 0.84 | HSD17B1 (0.59) | HSD17B1HSD17B2HTTSMN1; SMN2NPC1 | |
| SCHEMBL19295883 | 0.84 | HSD17B1 (0.58) | HSD17B1HSD17B2FASNHSD17B14CA12 | |
| SCHEMBL7717186 | 0.83 | FASN (0.72) | HSD17B1HSD17B2FASNDYRK1ADYRK1B | |
| SCHEMBL1758781 | 0.83 | HTT (0.75) | HSD17B1HSD17B2DYRK1ADYRK1BHTT | |
| SCHEMBL15851044 | 0.83 | HSD17B1 (0.57) | HSD17B1HSD17B2HSD17B14HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129395-B1 | ANISOTROPIC MELT POLYESTERS OF 6-HYDROXY-2-NAPHTHOIC ACID | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| EP-0169675-B1 | OPTICALLY ANISTROPIC MELT FORMING COPOLYESTERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0129395-A2 | Anisotropic melt polyesters of 6-hydroxy-2-naphthoic acid | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4447592-A | WITH DIACID AND DIHYDROXY, CARBO KETONE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-08 | — | — | US | disclosed |