SCHEMBL1758239

SCHEMBL1758239

Cc1cc(C(=O)c2ccc(O)c(C)c2)ccc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
HSD17B1 P14061 6/20 0.59
HSD17B2 P37059 6/20 0.59
SLC22A6 Q4U2R8 1/20 0.55
SLC22A8 Q8TCC7 1/20 0.55
DYRK1A Q13627 1/20 0.54
DYRK1B Q9Y463 1/20 0.54
TDP1 Q9NUW8 2/20 0.52
TP53 P04637 1/20 0.52
SIRT1 Q96EB6 1/20 0.50
LMNA P02545 2/20 0.48
NPC1 O15118 1/20 0.48
MITF O75030 1/20 0.48
POLB P06746 1/20 0.48
PDE10A Q9Y233 1/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPT P10636 1/20 0.47
ESR1 P03372 2/20 0.46
ESR2 Q92731 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31621156 1.00 HTT (0.61) HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6
SCHEMBL11053174 0.98 HTT (0.64) HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6
SCHEMBL31574429 0.96 HTT (0.57) HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6
SCHEMBL1758781 0.92 HTT (0.75) HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6
SCHEMBL17716507 0.92 SMN1; SMN2 (0.53) HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6
SCHEMBL9752047 0.90 SRD5A2 (0.59) HTTSMN1; SMN2HSD17B1HSD17B2DYRK1A
SCHEMBL5962849 0.90 HSD17B1 (0.64) HTTSMN1; SMN2HSD17B1HSD17B2TDP1
SCHEMBL3468499 0.88 HTT (0.55) HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6
SCHEMBL31574452 0.88 HTT (0.70) HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6
SCHEMBL15851085 0.88 HSD17B1 (0.58) HTTSMN1; SMN2HSD17B1HSD17B2DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110628013-B Bifunctional phosphorus-containing polyphenylene ether, and preparation method and application thereof 河北健馨生物科技有限公司 2022-06-24 CN claimed
EP-4726011-A1 FLAME RETARDANT, COMPOSITION, AND MOLDED ARTICLE ADEKA CORPORATION (JP) 2026-04-15 EP disclosed
EP-4678699-A1 RESIN ADDITIVE, COMPOSITION, MOLDED ARTICLE AND COMPOUND ADEKA CORPORATION (JP) 2026-01-14 EP disclosed
US-12503575-B2 Fine hollow particles comprising melamine-based resin KAGOSHIMA UNIVERSITY (JP) 2025-12-23 US disclosed
EP-3904079-B1 GAS BARRIER LAMINATE LINTEC CORP (JP) 2025-10-29 EP disclosed
CN-115335224-B Laminate for transparent conductive film, and method for producing transparent conductive film 琳得科株式会社 2025-01-03 CN disclosed
WO-2024252972-A1 FLAME RETARDANT, COMPOSITION, AND MOLDED ARTICLE 株式会社ADEKA 2024-12-12 WO disclosed
US-20240301171-A1 NOVEL FINE HOLLOW PARTICLES COMPRISING MELAMINE-BASED RESIN KAGOSHIMA UNIVERSITY (JP) 2024-09-12 US disclosed
WO-2024185557-A1 RESIN ADDITIVE, COMPOSITION, MOLDED ARTICLE AND COMPOUND 株式会社ADEKA 2024-09-12 WO disclosed
US-20240294734-A1 THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PRODUCING SHAPED BODY, SHAPED BODY AND USE OF RESIN MATERIAL ADEKA CORPORATION (JP) 2024-09-05 US disclosed
EP-0154506-B1 PREPARATION OF ORGANIC POLYMERS RAYCHEM LIMITED (GB) 1992-02-05 EP disclosed
US-4999411-A Polythioethers, polythiocarbonates, polythioamides, polythioimides RAYCHEM LIMITED (GB) 1991-03-12 US disclosed
US-4960835-A ENGINEERING THERMOPLASTICS RAYCHEM LIMITED (GB) 1990-10-02 US disclosed
US-4845179-A CONDENSATION POLYMERIZATION RAYCHEM LIMITED (GB) 1989-07-04 US disclosed
EP-0134204-B1 PROCESS FOR POLYMERISATION OF THERMOTROPIC POLYESTERS Monsanto Company (US) 1987-11-25 EP disclosed
EP-0154506-A2 Preparation of organic polymers RAYCHEM LIMITED (GB) 1985-09-11 EP disclosed
EP-0134204-A2 Process for polymerisation of thermotropic polyesters Monsanto Company (US) 1985-03-13 EP disclosed
US-4474938-A MOLECULAR WEIGHT CONTROL MONSANTO COMPANY (US) 1984-10-02 US disclosed
US-4371690-A POLYESTERS, POLYAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-02-01 US disclosed
US-4281106-A Heat-resistant, rigid polymers from difunctional 9,10-dihydro-9,10-ethanoanthracenes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-07-28 US disclosed