Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.64 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053174 | 0.92 | HTT (0.64) | HSD17B1HSD17B2PTGS1PTGS2TDP1 | |
| SCHEMBL1758239 | 0.90 | HTT (0.61) | HSD17B1HSD17B2TDP1SMN1; SMN2HTT | |
| SCHEMBL31621156 | 0.90 | HTT (0.61) | HSD17B1HSD17B2TDP1SMN1; SMN2HTT | |
| SCHEMBL9752047 | 0.89 | SRD5A2 (0.59) | HSD17B1HSD17B2PTGS2L3MBTL1SMN1; SMN2 | |
| SCHEMBL9752049 | 0.87 | HSD17B1 (0.59) | HSD17B1HSD17B2PTGS1PTGS2TDP1 | |
| SCHEMBL1758781 | 0.86 | HTT (0.75) | HSD17B1HSD17B2TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL31574429 | 0.86 | HTT (0.57) | HSD17B1HSD17B2TDP1SMN1; SMN2HTT | |
| SCHEMBL15851049 | 0.85 | HSD17B1 (0.60) | HSD17B1HSD17B2TDP1SMN1; SMN2HTT | |
| SCHEMBL10353029 | 0.85 | HSD17B1 (0.79) | HSD17B1HSD17B2SMN1; SMN2HTTNPC1 | |
| SCHEMBL3080812 | 0.85 | ATM (0.63) | HSD17B1HSD17B2PTGS1PTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590991-B1 | EPOXY RESIN COMPOSITION, PREPREG AND FIBER-REINFORCED COMPOSITE MATERIAL | TORAY INDUSTRIES (JP) | 2024-05-01 | — | — | EP | disclosed |
| CN-114805133-A | Aryl chloroformate preparation method | 苏州星日化学有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-110352207-A | Composition epoxy resin, prepreg and fibre reinforced composites | 东丽株式会社 | 2019-10-18 | — | — | CN | disclosed |
| EP-3029030-B1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | SUMITOMO CHEMICAL CO (JP) | 2019-09-04 | — | — | EP | disclosed |
| EP-2940012-B1 | TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-01-30 | — | — | EP | disclosed |
| EP-2940012-B1 | TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-01-30 | — | — | EP | disclosed |
| US-9983490-B2 | Electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-05-29 | — | — | US | disclosed |
| US-9983490-B2 | Electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-05-29 | — | — | US | disclosed |
| CN-105392779-B | Tetrazolinone compound and use thereof | 住友化学株式会社 | 2018-01-19 | — | — | CN | disclosed |
| US-9811012-B2 | Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus and process for producing electrophotographic photosensitive member | CANON KABUSHIKI KAISHA (JP) | 2017-11-07 | — | — | US | disclosed |
| EP-0410359-B1 | Substituted aminoalkoxy-benzene-derivatives | HOFFMANN LA ROCHE (CH) | 1994-01-26 | — | — | EP | disclosed |
| US-5214046-A | Synergistic mixtures, inhibitors of sterol biosynthesis | HOFFMANN-LA ROCHE INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5106878-A | Synergistic effects with other fungicides | HOFFMANN-LA ROCHE INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0410359-A1 | Substituted aminoalkoxy-benzene-derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| US-4692450-A | Phenyl-pyrimidinium, thiazolium or imidazolium salts and use in inhibiting intestinal resorption of cholesterol and bile salts | HOFFMANN-LA ROCHE INC. (US) | 1987-09-08 | — | — | US | disclosed |
| US-4675328-A | CHOLESTROL AND BILE SALTS | HOFFMANN-LAROCHE INC. (US) | 1987-06-23 | — | — | US | disclosed |
| CN-86100228-A | The preparation method of polycyclic salts | — | 1986-10-29 | — | — | CN | disclosed |
| EP-0189094-A2 | Polycyclic salts | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-07-30 | — | — | EP | disclosed |
| US-4329360-A | Benzophenones and their use as fungicides | GAF CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |
| US-4230624-A | CYCLIZATION, BASIC CATALYSTS | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (FR) | 1980-10-28 | — | — | US | disclosed |