Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758239 | 0.98 | HTT (0.61) | HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6 | |
| SCHEMBL31621156 | 0.98 | HTT (0.61) | HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6 | |
| SCHEMBL1758781 | 0.94 | HTT (0.75) | HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6 | |
| SCHEMBL31574429 | 0.93 | HTT (0.57) | HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6 | |
| SCHEMBL9752047 | 0.92 | SRD5A2 (0.59) | HTTSMN1; SMN2HSD17B1HSD17B2SIRT1 | |
| SCHEMBL5962849 | 0.92 | HSD17B1 (0.64) | HTTSMN1; SMN2HSD17B1HSD17B2LMNA | |
| SCHEMBL3468499 | 0.90 | HTT (0.55) | HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6 | |
| SCHEMBL15851085 | 0.90 | HSD17B1 (0.58) | HTTSMN1; SMN2HSD17B1HSD17B2SIRT1 | |
| SCHEMBL31574447 | 0.90 | HTT (0.70) | HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6 | |
| SCHEMBL31574452 | 0.90 | HTT (0.70) | HTTSMN1; SMN2HSD17B1HSD17B2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026991-B1 | AROMATIC POLYESTER AND FILAMENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4276226-A | Methyl- and chloro- substituted aromatic diketodiols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-30 | — | — | US | disclosed |
| US-4269965-A | COMPRISING MONOMERS OF P-HYDROXYBENZOIC ACID, 3,4'-DIHYDROXYBENZOPHENONE OR TEREPHTHALOYLDI(3-METHYL-4-HYDROXYBENZENE, AND TEREPHTHALIC ACID; LUSTER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
| EP-0026991-A1 | Aromatic polyester and filaments | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-04-15 | — | — | EP | disclosed |