Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 8/20 | 0.61 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352927 | 0.80 | NOTUM (0.60) | NOTUMHSD17B3POLB | |
| SCHEMBL5793078 | 0.76 | NOTUM (1.00) | NOTUMHSD17B3ALDH1A1LMNAKMT2A | |
| SCHEMBL5795715 | 0.76 | NOTUM (1.00) | NOTUMHSD17B3ALDH1A1LMNAKMT2A | |
| SCHEMBL5009163 | 0.73 | NOTUM (1.00) | NOTUMHSD17B3MAPTPOLBTRIM24 | |
| SCHEMBL11147651 | 0.72 | NOTUM (0.66) | NOTUMHSD17B3MAPTPOLBTRIM24 | |
| SCHEMBL28984695 | 0.67 | NOTUM (0.60) | NOTUMHSD17B3MAPTAVPR1A | |
| SCHEMBL8870414 | 0.67 | NOX1 (0.73) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL10353391 | 0.67 | LMNA (0.57) | NOTUMHSD17B3MAPTMEN1ALDH1A1 | |
| SCHEMBL11142890 | 0.67 | NOTUM (0.61) | NOTUMHSD17B3MAPTPOLBTRIM24 | |
| SCHEMBL11142887 | 0.67 | NOTUM (0.61) | NOTUMHSD17B3MAPTPOLBTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292824-B1 | PROCESS FOR THE NUCLEAR CHLORINATION OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4851596-A | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0292824-A1 | Process for the nuclear chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |