Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911135 | 0.92 | HRH1 (0.60) | LOXL2HRH1SIGMAR1ROCK1MEN1 | |
| SCHEMBL7360165 | 0.89 | LOXL2 (0.54) | LOXL2HRH1SIGMAR1ROCK1TDP1 | |
| SCHEMBL20689752 | 0.85 | SIGMAR1 (0.59) | LOXL2HRH1SIGMAR1ALDH1A1 | |
| SCHEMBL3976803 | 0.81 | ALDH1A1 (0.54) | LOXL2HRH1TDP1ALDH1A1MEN1 | |
| SCHEMBL2566281 | 0.80 | SIGMAR1 (0.47) | LOXL2HRH1SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13102158 | 0.79 | ALDH1A1 (0.50) | LOXL2SIGMAR1TDP1ALDH1A1MEN1 | |
| SCHEMBL7724204 | 0.79 | SIGMAR1 (0.78) | SIGMAR1 | |
| SCHEMBL2185893 | 0.79 | SIGMAR1 (0.68) | SIGMAR1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3624033 | 0.78 | SIGMAR1 (0.72) | LOXL2SIGMAR1ALDH1A1CA12SMN1; SMN2 | |
| SCHEMBL1319729 | 0.78 | HRH1 (0.83) | LOXL2HRH1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198140-B1 | OPTICAL DATA STORAGE MEDIUM HAVING CHROMOPHORE/POLYMER COORDINATED INFORMATION LAYER | CELANESE CORPORATION (US) | 1990-08-08 | — | — | EP | disclosed |
| EP-0154178-B1 | NITROMETHYLENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND INSECTICIDAL, MITICIDAL AND NEMATICIDAL AGENTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4680294-A | Pesticidal novel nitromethylene derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-07-14 | — | — | US | disclosed |
| US-4647570-A | Pesticidal novel nitromethylene derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-03-03 | — | — | US | disclosed |
| EP-0094766-B1 | QUINAZOLINE CARDIAC STIMULANTS | Pfizer Limited (GB) | 1986-12-30 | — | — | EP | disclosed |
| EP-0198140-A2 | Optical data storage medium having chromophore/polymer coordinated information layer | CELANESE CORPORATION (US) | 1986-10-22 | — | — | EP | disclosed |
| US-4605607-A | Optical data storage medium having organometallic chromophore/polymer coordinated information layer | CELANESE CORPORATION (US) | 1986-08-12 | — | — | US | disclosed |
| EP-0154178-A1 | Nitromethylene derivatives, method for their preparation and insecticidal, miticidal and nematicidal agents | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-09-11 | — | — | EP | disclosed |
| US-4489075-A | Cyclic sulfonamidoalkyl substituted 4-piperidinoquinazoline cardiac stimulants | PFIZER INC. (US) | 1984-12-18 | — | — | US | disclosed |
| EP-0094766-A2 | Quinazoline cardiac stimulants | Pfizer Limited (GB) | 1983-11-23 | — | — | EP | disclosed |