Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355266 | 0.79 | SLC2A1 (0.42) | ALDH1A1KDM4EHPGDCCNB2CDK1 | |
| Hydrochloric Acid SCHEMBL10355348 | 0.78 | SLC2A1 (0.41) | ALDH1A1KDM4EHPGDCCNB2CDK1 | |
| SCHEMBL10999375 | 0.76 | MAPK13 (0.48) | ALDH1A1KDM4EHPGDGCGRMAPK14 | |
| SCHEMBL10355416 | 0.75 | MAPT (0.42) | ALDH1A1KDM4EHPGDGCGRMAPK14 | |
| Hydrochloric Acid SCHEMBL10355378 | 0.74 | MAPT (0.41) | ALDH1A1KDM4EHPGDGCGRMAPK14 | |
| SCHEMBL10355369 | 0.74 | DHPS (0.48) | ALDH1A1KDM4EHPGDGCGRMAPK14 | |
| SCHEMBL7041734 | 0.73 | KDM4E (0.67) | KDM4EHPGDCCNB2CDK1CCNB1 | |
| SCHEMBL10355417 | 0.73 | CYP1A2 (0.54) | ALDH1A1KDM4EHPGDCCNB2CDK1 | |
| Hydrochloric Acid SCHEMBL10355415 | 0.73 | DHPS (0.47) | ALDH1A1KDM4EHPGDGCGRMAPK14 | |
| Hydrochloric Acid SCHEMBL10355308 | 0.72 | CYP1A2 (0.53) | ALDH1A1KDM4EHPGDCCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074130-B1 | NEW IMIDAZOLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON S.p.A. (IT) | 1990-09-19 | — | — | EP | claimed |
| US-4560696-A | Analgesic, antipyretic or anti-inflammatory imidazole compounds | ZAMBON S.P.A. (IT) | 1985-12-24 | — | — | US | claimed |
| EP-0074130-A2 | New imidazole compounds, process for the preparation thereof and pharmaceutical compositions containing them | ZAMBON S.p.A. (IT) | 1983-03-16 | — | — | EP | claimed |