Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10355378 | 0.99 | MAPT (0.41) | MAPTTP53CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10355417 | 0.89 | CYP1A2 (0.54) | MAPTTP53CYP1A2CYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL10355308 | 0.88 | CYP1A2 (0.53) | MAPTTP53CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10355369 | 0.87 | DHPS (0.48) | MAPTTP53L3MBTL1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL10355415 | 0.86 | DHPS (0.47) | MAPTTP53L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL10999375 | 0.84 | MAPK13 (0.48) | MAPTCYP1A2CYP3A4SMN1; SMN2HPGD | |
| SCHEMBL10355266 | 0.82 | SLC2A1 (0.42) | CYP1A2CYP2C19SMN1; SMN2HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL10355348 | 0.81 | SLC2A1 (0.41) | CYP1A2CYP2C19SMN1; SMN2HPGDKDM4E | |
| SCHEMBL10355386 | 0.75 | ALDH1A1 (0.44) | MAPTTP53CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL7041734 | 0.70 | KDM4E (0.67) | SMN1; SMN2HPGDKDM4EGCGRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074130-B1 | NEW IMIDAZOLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON S.p.A. (IT) | 1990-09-19 | — | — | EP | claimed |
| EP-0074130-B1 | NEW IMIDAZOLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON S.p.A. (IT) | 1990-09-19 | — | — | EP | disclosed |
| US-4560696-A | Analgesic, antipyretic or anti-inflammatory imidazole compounds | ZAMBON S.P.A. (IT) | 1985-12-24 | — | — | US | disclosed |
| EP-0074130-A2 | New imidazole compounds, process for the preparation thereof and pharmaceutical compositions containing them | ZAMBON S.p.A. (IT) | 1983-03-16 | — | — | EP | disclosed |