SCHEMBL1035644

SCHEMBL1035644

Cc1cc(C)c(C(=O)P(=O)(CC(=O)Oc2ccccc2)C(=O)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
POLB P06746 1/20 0.38
HPGD P15428 2/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.37
CYP19A1 P11511 1/20 0.36
ELANE P08246 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PTK2B Q14289 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
HCRTR1 O43613 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1037982 0.81 ALDH1A1 (0.45) LMNAMAPK1KMT2A
SCHEMBL1030595 0.79 POLB (0.40) LMNAPOLBHPGDMEN1KMT2A
SCHEMBL1038176 0.78 LMNA (0.47) LMNAPOLBHPGDMAPK1MEN1
SCHEMBL1039014 0.78 NLRP3 (0.44) LMNAHPGDGAAMAPK1MEN1
SCHEMBL1032446 0.77 GAA (0.42) LMNAPOLBHPGDGAAMAPK1
SCHEMBL2710988 0.76 GAA (0.41) LMNAPOLBHPGDGAAMAPK1
SCHEMBL1038337 0.75 KDM4E (0.40) LMNAPOLBHPGDNPSR1MEN1
SCHEMBL7625246 0.75 LMNA (0.41) LMNAPOLBHPGDMEN1KMT2A
SCHEMBL13811188 0.75 HPGD (0.46) LMNAHPGDNPSR1MEN1KMT2A
SCHEMBL28465879 0.75 HPGD (0.46) LMNAPOLBHPGDNPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1814891-B1 BISACYLPHOSPHANES AND THEIR USE AS PHOTOINITIATORS; PROCESS FOR PREPARING ACYLPHOSPHANES BASF SE (DE) 2011-01-26 EP disclosed