SCHEMBL1035659

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1032847	0.85	NPC1 (0.50)	CHRNB2CHRNB4CHRNA3CHRNA4MEN1
	SCHEMBL1031275	0.82	CYP1A2 (0.52)	MEN1KMT2AKDM4EL3MBTL1ALDH1A1
	SCHEMBL1034675	0.81	ALDH1A1 (0.50)	MEN1KMT2AKDM4EALDH1A1SMN1; SMN2
	SCHEMBL1033871	0.77	FGFR4 (0.51)	CHRNB2CHRNB4CHRNA3CHRNA4MEN1
	SCHEMBL1033965	0.77	CHRNB2 (0.52)	CHRNB2CHRNB4CHRNA3CHRNA4MEN1
	SCHEMBL1034456	0.76	FGFR4 (0.48)	CHRNB2CHRNB4CHRNA3CHRNA4MEN1
	SCHEMBL27486980	0.76	MEN1 (0.63)	CHRNB2CHRNB4CHRNA3CHRNA4MEN1
	SCHEMBL30417052	0.76	MEN1 (0.63)	CHRNB2CHRNB4CHRNA3CHRNA4MEN1
	Malonic Acid SCHEMBL30417293	0.76	MEN1 (0.59)	CHRNB2CHRNB4CHRNA3CHRNA4MEN1
	Hydrochloric Acid SCHEMBL30416887	0.75	MEN1 (0.61)	CHRNB2CHRNB4CHRNA3CHRNA4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.