Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | DNM2 | P50570 | 11/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110422 | 0.80 | CYP2C19 (0.49) | CYP2C19HRH3DNM2HRH4 | |
| SCHEMBL1318627 | 0.80 | CYP2C19 (0.49) | CYP2C19HRH3DNM2HRH4L3MBTL1 | |
| SCHEMBL1752801 | 0.77 | SYK (0.41) | — | |
| SCHEMBL20037454 | 0.77 | IL1B (0.45) | CYP2C19 | |
| SCHEMBL1110459 | 0.75 | CYP2C19 (0.47) | CYP2C19HRH3DNM2NCF1HRH4 | |
| SCHEMBL15382053 | 0.74 | HCAR3 (0.46) | CYP2C19NCF1 | |
| SCHEMBL8046837 | 0.74 | HRH3 (0.45) | HRH3 | |
| SCHEMBL12895618 | 0.74 | HCAR3 (0.39) | — | |
| SCHEMBL23768365 | 0.73 | SOAT1 (0.49) | DNM2 | |
| SCHEMBL6027125 | 0.73 | CYP2C19 (0.57) | CYP2C19HRH3DNM2NCF1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121600-B1 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-07-18 | — | — | EP | disclosed |