Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 5/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | ESRRG | P62508 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785944 | 0.85 | CHRM3 (0.41) | TSHRCHRM3SCN5ASCN9AKIF11 | |
| SCHEMBL10356413 | 0.84 | ESR1 (0.42) | CYP19A1ESR1ESR2 | |
| SCHEMBL10356346 | 0.83 | ESR1 (0.39) | ESR1ESR2ALOX5 | |
| SCHEMBL10356406 | 0.83 | ESR1 (0.40) | ESR1ESR2 | |
| SCHEMBL10789110 | 0.82 | SCN5A (0.45) | TSHRCHRM3SCN5ASCN9AKIF11 | |
| SCHEMBL11618396 | 0.77 | KIF11 (0.49) | CHRM3SCN5ASCN9AKIF11CYP19A1 | |
| SCHEMBL10356747 | 0.75 | ESR1 (0.39) | TSHRESR1ESR2ALOX5 | |
| SCHEMBL10356402 | 0.75 | KIF11 (0.42) | KIF11ESR1ESR2 | |
| SCHEMBL11373504 | 0.72 | BCL2 (0.42) | TSHRCYP19A1ESR1ESR2 | |
| SCHEMBL10356407 | 0.71 | TTR (0.43) | TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112587-B1 | DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-19 | — | — | EP | claimed |
| EP-0112587-A2 | Derivatives of 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcine, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | claimed |
| EP-0112587-B1 | DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-19 | — | — | EP | disclosed |
| US-4510338-A | TREATMENT OF ACUTE ETHANOLIC INTOXICATION/- | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1985-04-09 | — | — | US | disclosed |
| EP-0112587-A2 | Derivatives of 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcine, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | disclosed |