Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356402 | 0.87 | KIF11 (0.42) | ESR1ESR2CYP3A4CYP2D6 | |
| SCHEMBL10356346 | 0.83 | ESR1 (0.39) | ESR1ESR2CYP3A4ALDH1A1HTT | |
| SCHEMBL10356950 | 0.83 | TSHR (0.41) | ESR1ESR2 | |
| SCHEMBL10740804 | 0.82 | ESR1 (0.47) | ESR1ESR2MAPTALDH1A1MEN1 | |
| SCHEMBL10356748 | 0.79 | ESR1 (0.36) | ESR1ESR2TRPV1IDO1NOS3 | |
| SCHEMBL10356747 | 0.78 | ESR1 (0.39) | ESR1ESR2CYP3A4CYP2D6MAPT | |
| Flumecinol SCHEMBL667363 | 0.77 | ALDH1A1 (0.45) | CYP3A4CYP2D6MAPTALDH1A1MEN1 | |
| SCHEMBL10356413 | 0.75 | ESR1 (0.42) | ESR1ESR2MAPTMEN1KMT2A | |
| Propane SCHEMBL3966641 | 0.72 | IDO1 (0.47) | ESR1ESR2CYP3A4MAPTALDH1A1 | |
| SCHEMBL10356407 | 0.71 | TTR (0.43) | CYP3A4MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112587-B1 | DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-19 | — | — | EP | claimed |
| EP-0112587-B1 | DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-19 | — | — | EP | disclosed |
| EP-0116234-B1 | CARBAMYLOXYBENZHYDROLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1986-03-26 | — | — | EP | disclosed |
| US-4564630-A | ANTILIPEMIC AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-01-14 | — | — | US | disclosed |
| US-4510338-A | TREATMENT OF ACUTE ETHANOLIC INTOXICATION/- | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1985-04-09 | — | — | US | disclosed |
| EP-0116234-A1 | Carbamyloxybenzhydrole derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-22 | — | — | EP | disclosed |
| EP-0112587-A2 | Derivatives of 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcine, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | disclosed |