Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356747 | 0.88 | ESR1 (0.39) | ESR1ESR2ARCYP3A4CYP2D6 | |
| SCHEMBL10356406 | 0.87 | ESR1 (0.40) | ESR1ESR2CYP3A4CYP2D6 | |
| SCHEMBL10356413 | 0.84 | ESR1 (0.42) | ESR1ESR2AR | |
| SCHEMBL10356346 | 0.84 | ESR1 (0.39) | ESR1ESR2CYP3A4 | |
| SCHEMBL10784877 | 0.81 | KIF11 (0.57) | KIF11PTGS1ESR1ESR2AR | |
| SCHEMBL10356748 | 0.80 | ESR1 (0.36) | KIF11ESR1ESR2AR | |
| SCHEMBL27911913 | 0.75 | AOC3 (0.42) | ESR2CYP3A4 | |
| SCHEMBL10356950 | 0.75 | TSHR (0.41) | KIF11ESR1ESR2 | |
| SCHEMBL10784573 | 0.74 | ESR1 (0.44) | KIF11ESR1ESR2ARCYP3A4 | |
| SCHEMBL10740804 | 0.73 | ESR1 (0.47) | KIF11ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112587-B1 | DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-19 | — | — | EP | claimed |
| EP-0112587-A2 | Derivatives of 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcine, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | claimed |
| EP-0112587-B1 | DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-19 | — | — | EP | disclosed |
| US-4510338-A | TREATMENT OF ACUTE ETHANOLIC INTOXICATION/- | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1985-04-09 | — | — | US | disclosed |
| EP-0112587-A2 | Derivatives of 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcine, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | disclosed |