Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356402 | 0.84 | KIF11 (0.42) | ESR1ESR2CYP3A4 | |
| SCHEMBL10356413 | 0.84 | ESR1 (0.42) | ESR1ESR2SMN1; SMN2LMNAHTT | |
| SCHEMBL10356747 | 0.84 | ESR1 (0.39) | ESR1ESR2ALOX5CYP3A4SMN1; SMN2 | |
| SCHEMBL10356950 | 0.83 | TSHR (0.41) | ESR1ESR2ALOX5 | |
| SCHEMBL10356406 | 0.83 | ESR1 (0.40) | ESR1ESR2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL10816937 | 0.82 | ALDH1A1 (0.47) | ESR1ESR2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL10356407 | 0.80 | TTR (0.43) | ALDH1A1CYP3A4LMNAALOX15HSD17B10 | |
| SCHEMBL10356748 | 0.80 | ESR1 (0.36) | ESR1ESR2TYR | |
| SCHEMBL10598204 | 0.78 | ESR1 (0.57) | ESR1ESR2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL11627229 | 0.78 | KIF11 (0.33) | ESR1ESR2ALDH1A1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112587-B1 | DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-19 | — | — | EP | claimed |
| EP-0112587-B1 | DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-19 | — | — | EP | disclosed |
| EP-0112587-A2 | Derivatives of 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcine, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | disclosed |